Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G1B | P04054 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CACNA2D1 | P54289 | 10/20 | 0.32 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8569449 | 0.85 | PLA2G1B (0.40) | PLA2G1BPLA2G2ASIGMAR1MEN1POLB | |
| SCHEMBL23451697 | 0.80 | SIGMAR1 (0.42) | PLA2G1BPLA2G2ASIGMAR1NPSR1CACNA2D1 | |
| SCHEMBL1147313 | 0.80 | PLA2G1B (0.56) | PLA2G1BPLA2G2ASIGMAR1NPSR1CACNA2D1 | |
| SCHEMBL417108 | 0.78 | OPRM1 (0.50) | PLA2G1BPLA2G2ASIGMAR1NPSR1CACNA2D1 | |
| SCHEMBL3856955 | 0.78 | OPRM1 (0.50) | PLA2G1BPLA2G2ASIGMAR1NPSR1CACNA2D1 | |
| SCHEMBL29881540 | 0.78 | OPRM1 (0.50) | PLA2G1BPLA2G2ASIGMAR1NPSR1CACNA2D1 | |
| SCHEMBL23451616 | 0.78 | SIGMAR1 (0.41) | PLA2G1BPLA2G2ASIGMAR1NPSR1CACNA2D1 | |
| SCHEMBL23451750 | 0.78 | SIGMAR1 (0.41) | PLA2G1BPLA2G2ASIGMAR1NPSR1CACNA2D1 | |
| SCHEMBL3856709 | 0.78 | OPRM1 (0.50) | PLA2G1BPLA2G2ASIGMAR1NPSR1CACNA2D1 | |
| SCHEMBL20828858 | 0.76 | PLA2G1B (0.42) | PLA2G1BPLA2G2ASIGMAR1NPSR1CACNA2D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114773278-A | Quinazoline compound and application thereof in antivirus | 苏州大学 | 2022-07-22 | — | — | CN | claimed |
| CN-114773278-A | Quinazoline compound and application thereof in antivirus | 苏州大学 | 2022-07-22 | — | — | CN | disclosed |