Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11985077 | 0.90 | TSHR (0.50) | ALDH1A1LMNAKMT2ATDP1MEN1 | |
| SCHEMBL28817917 | 0.86 | HDAC4 (0.57) | ALDH1A1LMNAKMT2AMEN1TSHR | |
| SCHEMBL446918 | 0.86 | ALDH1A1 (0.57) | ALDH1A1MAOBLMNAKMT2ATDP1 | |
| SCHEMBL19442031 | 0.85 | HTT (0.40) | ALDH1A1LMNAKMT2ATDP1MEN1 | |
| SCHEMBL21594660 | 0.83 | ALDH1A1 (0.50) | ALDH1A1MAOBLMNATDP1TSHR | |
| SCHEMBL18104617 | 0.83 | HTT (0.56) | ALDH1A1MAOBLMNAKMT2ATDP1 | |
| SCHEMBL19442030 | 0.83 | ALDH1A1 (0.50) | ALDH1A1LMNACHRM1KDM4EMAPT | |
| SCHEMBL28655961 | 0.81 | HDAC4 (0.63) | ALDH1A1MAOBLMNAKMT2ATDP1 | |
| SCHEMBL19825336 | 0.81 | TSHR (0.43) | ALDH1A1LMNAKMT2ATDP1MEN1 | |
| SCHEMBL19825337 | 0.80 | TSHR (0.45) | ALDH1A1KMT2ATDP1MEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114773299-A | Preparation method of 2, 5-disubstituted furan compound | 中国科学院宁波材料技术与工程研究所 | 2022-07-22 | — | — | CN | disclosed |