Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.59 |
| ▸ | MAPT | P10636 | 9/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 7/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.55 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.55 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.55 |
| ▸ | KDM1A | O60341 | 1/20 | 0.51 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.47 |
| ▸ | VCP | P55072 | 2/20 | 0.47 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28007919 | 0.86 | ADRB2 (0.55) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL27812589 | 0.85 | ADRB2 (0.67) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL28787879 | 0.84 | MAPT (0.64) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A | |
| Bromide SCHEMBL27812101 | 0.84 | ADRB2 (0.65) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL28007948 | 0.84 | MAPT (0.62) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A | |
| Bromide SCHEMBL27832198 | 0.83 | MAPT (0.62) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL20705453 | 0.83 | MAPT (0.53) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL27832203 | 0.82 | ADRB2 (0.52) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL18739882 | 0.81 | ADRB2 (0.54) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL1527377 | 0.81 | GAA (0.61) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104530035-A | 5-piperonyl-4-alkyl-2-aromatic aminothiazole and preparing method and application thereof | UNIV HUNAN | 2015-04-22 | — | — | CN | claimed |
| CN-104530035-A | 5-piperonyl-4-alkyl-2-aromatic aminothiazole and preparing method and application thereof | UNIV HUNAN | 2015-04-22 | — | — | CN | disclosed |