Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | KDM1A | O60341 | 1/20 | 0.55 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.51 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.51 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.49 |
| ▸ | CTPS1 | P17812 | 5/20 | 0.48 |
| ▸ | CPB1 | P15086 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CFTR | P13569 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28818145 | 0.84 | ALDH1A1 (0.59) | MAPTGAAKDM1AADRB2ADRB1 | |
| SCHEMBL27812589 | 0.84 | ADRB2 (0.67) | MAPTGAAADRB2ADRB1ADRB3 | |
| SCHEMBL28787879 | 0.82 | MAPT (0.64) | MAPTGAAADRB2ADRB1ADRB3 | |
| Bromide SCHEMBL27812101 | 0.82 | ADRB2 (0.65) | MAPTGAAADRB2ADRB1ADRB3 | |
| SCHEMBL28007623 | 0.81 | VCP (0.54) | MAPTGAAADRB2ADRB1ADRB3 | |
| Bromide SCHEMBL27832198 | 0.81 | MAPT (0.62) | MAPTGAAADRB2ADRB1ADRB3 | |
| SCHEMBL491436 | 0.80 | ADRB2 (0.72) | MAPTGAAADRB2ADRB1ADRB3 | |
| SCHEMBL28007593 | 0.79 | PLA2G7 (0.60) | MAPTGAAADRB2ADRB1ADRB3 | |
| SCHEMBL5494002 | 0.79 | ADRB2 (0.74) | MAPTGAAADRB2ADRB1ADRB3 | |
| SCHEMBL28007897 | 0.76 | NPC1 (0.60) | MAPTKDM1AADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104530035-A | 5-piperonyl-4-alkyl-2-aromatic aminothiazole and preparing method and application thereof | UNIV HUNAN | 2015-04-22 | — | — | CN | claimed |
| CN-104530035-A | 5-piperonyl-4-alkyl-2-aromatic aminothiazole and preparing method and application thereof | UNIV HUNAN | 2015-04-22 | — | — | CN | disclosed |