Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.70 |
| ▸ | ALPI | P09923 | 1/20 | 0.57 |
| ▸ | CISD1 | Q9NZ45 | 3/20 | 0.54 |
| ▸ | MAOA | P21397 | 2/20 | 0.54 |
| ▸ | MAOB | P27338 | 2/20 | 0.54 |
| ▸ | PIM1 | P11309 | 1/20 | 0.54 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.54 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.49 |
| ▸ | PNP | P00491 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | BLM | P54132 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | APAF1 | O14727 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29727412 | 1.00 | LMNA (0.70) | LMNAMAPK1SMN1; SMN2HSD17B10ALPI | |
| SCHEMBL19748980 | 0.83 | LMNA (1.00) | LMNAMAPK1SMN1; SMN2HSD17B10ALPI | |
| SCHEMBL19748978 | 0.83 | LMNA (1.00) | LMNAMAPK1SMN1; SMN2HSD17B10ALPI | |
| SCHEMBL31667454 | 0.83 | LMNA (1.00) | LMNAMAPK1SMN1; SMN2HSD17B10ALPI | |
| SCHEMBL19387247 | 0.83 | LMNA (1.00) | LMNAMAPK1SMN1; SMN2HSD17B10ALPI | |
| SCHEMBL29727411 | 0.83 | LMNA (1.00) | LMNAMAPK1SMN1; SMN2HSD17B10ALPI | |
| SCHEMBL22625264 | 0.80 | MAPT (0.69) | LMNAMAPK1SMN1; SMN2HSD17B10ALPI | |
| SCHEMBL6670159 | 0.79 | MEN1 (0.67) | LMNAMAPK1SMN1; SMN2ALPICISD1 | |
| SCHEMBL6670153 | 0.79 | MEN1 (0.67) | LMNAMAPK1SMN1; SMN2ALPICISD1 | |
| SCHEMBL249297 | 0.77 | PLK4 (0.70) | LMNAMAPK1SMN1; SMN2PIM1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109912492-B | Synthetic method of 3-benzylidene isoindoline-1-one derivative | 大连理工大学 | 2022-06-14 | — | — | CN | disclosed |