Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.39 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.37 |
| ▸ | CA3 | P07451 | 2/20 | 0.36 |
| ▸ | CA5A | P35218 | 2/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22716360 | 0.86 | LMNA (0.36) | LMNASLC22A6TSHRNFKB1PMP22 | |
| SCHEMBL10247191 | 0.78 | LMNA (0.42) | LMNASLC22A6TSHRNFKB1PMP22 | |
| SCHEMBL112741 | 0.78 | LMNA (0.59) | LMNASLC22A6TSHRNFKB1PMP22 | |
| SCHEMBL27006782 | 0.77 | CA3 (0.48) | CA3CA5ACA5BCA12CA2 | |
| SCHEMBL345581 | 0.77 | EGLN1 (0.33) | LMNASLC22A6 | |
| SCHEMBL19177664 | 0.76 | S1PR1 (0.33) | LMNASLC22A6TSHRNFKB1PMP22 | |
| SCHEMBL1741769 | 0.76 | LMNA (0.56) | LMNASLC22A6TSHRNFKB1PMP22 | |
| SCHEMBL11896840 | 0.76 | LMNA (0.56) | LMNASLC22A6TSHRNFKB1PMP22 | |
| Hydrochloric Acid SCHEMBL16057049 | 0.75 | EGLN1 (0.32) | LMNAGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL2468753 | 0.74 | LMNA (0.53) | LMNASLC22A6TSHRNFKB1PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104662015-A | Complement pathway modulators and uses thereof | NOVARTIS AG | 2015-05-27 | — | — | CN | disclosed |