Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.56 |
| ▸ | CA1 | P00915 | 3/20 | 0.56 |
| ▸ | CA2 | P00918 | 3/20 | 0.56 |
| ▸ | CA7 | P43166 | 3/20 | 0.56 |
| ▸ | CA9 | Q16790 | 3/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
| ▸ | ALPL | P05186 | 2/20 | 0.43 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4260262 | 0.85 | CYP4F2 (0.52) | KMT2AALPLNPC1RAB9AMAPT | |
| SCHEMBL4503149 | 0.80 | ACMSD (0.53) | CA12CA1CA2CA7CA9 | |
| SCHEMBL13675152 | 0.77 | HSD17B1 (0.47) | CA12CA9KMT2AALPLGAA | |
| SCHEMBL6260431 | 0.76 | CA12 (0.64) | CA12CA1CA2CA7CA9 | |
| SCHEMBL27795467 | 0.74 | TSHR (0.55) | NPC1RAB9AMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL9999709 | 0.73 | CA12 (0.60) | CA12CA1CA2CA7CA9 | |
| SCHEMBL7360724 | 0.73 | TSHR (0.57) | KMT2AMAPTALDH1A1KDM4ETSHR | |
| SCHEMBL29457603 | 0.73 | CA12 (1.00) | CA12CA1CA2CA7CA9 | |
| SCHEMBL1641611 | 0.73 | CA12 (0.74) | CA12CA1CA2CA7CA9 | |
| SCHEMBL39259 | 0.73 | CA12 (1.00) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104610147-A | Preparation method of benzene substituted pyrazole derivative | Hunan huateng pharmaceutical co ltd | 2015-05-13 | — | — | CN | disclosed |