Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | MEN1 | O00255 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.35 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28014355 | 0.85 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL29414896 | 0.77 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL29414899 | 0.77 | PDE7A (0.45) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL24168282 | 0.77 | PDE7A (0.45) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL1192691 | 0.77 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL28305924 | 0.75 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL15015164 | 0.74 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL30127305 | 0.74 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL30127582 | 0.74 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL29414902 | 0.74 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104557688-A | Synthetic method for Sorafenib intermediate and synthetic method for compound A used for synthesizing Sorafenib intermediate | ASYMCHEM LAB TIANJIN CO LTD | 2015-04-29 | — | — | CN | disclosed |