Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 2/20 | 0.33 |
| ▸ | ACP3 | P15309 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.32 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
| ▸ | MMP14 | P50281 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
| ▸ | ERN1 | O75460 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL547450 | 0.73 | PTPN1 (0.39) | L3MBTL1POLBPTPN1MEN1KMT2A | |
| SCHEMBL6001561 | 0.69 | ALDH1A1 (0.38) | POLBPTPN1MEN1KMT2A | |
| SCHEMBL6013736 | 0.67 | HSD17B10 (0.33) | POLBPTPN1MEN1KMT2ACA14 | |
| SCHEMBL10944396 | 0.67 | HSD17B10 (0.37) | L3MBTL1MEN1KMT2A | |
| SCHEMBL98430 | 0.66 | PTPN1 (0.42) | L3MBTL1POLBPTPN1MEN1KMT2A | |
| SCHEMBL29529441 | 0.66 | ALDH1A1 (0.41) | POLB | |
| SCHEMBL28244381 | 0.66 | ALDH1A1 (0.35) | — | |
| SCHEMBL5359604 | 0.66 | ALDH1A1 (0.31) | — | |
| SCHEMBL27560293 | 0.66 | ALDH1A1 (0.31) | — | |
| SCHEMBL27626197 | 0.65 | PTPN1 (0.41) | L3MBTL1POLBPTPN1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102762549-B | Phthalazinone derivative, and preparation method and pharmaceutical use thereof | SHANGHAI HENGRUI PHARM CO LTD | 2015-05-27 | — | — | CN | disclosed |