Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6001561 | 0.77 | ALDH1A1 (0.38) | ALDH1A1CYP2A6TSHRHSD17B10TDP1 | |
| SCHEMBL28244381 | 0.74 | ALDH1A1 (0.35) | ALDH1A1CYP2A6TSHRHSD17B10TDP1 | |
| SCHEMBL29529441 | 0.74 | ALDH1A1 (0.41) | ALDH1A1CYP2A6TSHRHSD17B10TDP1 | |
| SCHEMBL27560293 | 0.73 | ALDH1A1 (0.31) | ALDH1A1CYP2A6TSHRHSD17B10TDP1 | |
| SCHEMBL547450 | 0.73 | PTPN1 (0.39) | ALDH1A1CYP2A6TSHRHSD17B10TDP1 | |
| SCHEMBL6013736 | 0.71 | HSD17B10 (0.33) | ALDH1A1CYP2A6TSHRHSD17B10TDP1 | |
| SCHEMBL10944396 | 0.70 | HSD17B10 (0.37) | ALDH1A1HSD17B10TDP1 | |
| SCHEMBL221413 | 0.69 | ALDH1A1 (0.35) | ALDH1A1CYP2A6TSHRHSD17B10TDP1 | |
| SCHEMBL9564638 | 0.67 | KMT2A (0.42) | ALDH1A1HSD17B10TDP1 | |
| SCHEMBL27610609 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7217723-B2 | Substituted benzothiophenes, e.g., 7Z)-7-hydroxyimino-4,5,6,7-tetrahydro-benzo[b]thiophene-3-sulfonic acid [2-(4-fluorophenyl)-2-hydroxyethyl]-methyl-amide; treating allergies such as atopic dermatitis, allergic coryza, bronchial asthma, hypersensitive pneumoniac and pulmonary aspergillosis. | EISAI CO., LTD. (JP) | 2007-05-15 | — | — | US | disclosed |
| US-20050227959-A1 | Heterocyclic compound having oxime group | EISAI CO., LTD. (JP) | 2005-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050227959-A1 | Heterocyclic compound having oxime group | STAT6, HRH4, HRH2 | ALDH1A1 1391/4885CYP2A6 349/4885TSHR 284/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.