Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 4/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.41 |
| ▸ | MAP3K14 | Q99558 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | NSD1 | Q96L73 | 1/20 | 0.35 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.35 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.35 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28819563 | 0.99 | NR1H4 (0.45) | NR1H4MAPK10HCRTR1HCRTR2MAP3K14 | |
| SCHEMBL28819648 | 0.87 | NR1H4 (0.45) | NR1H4MAPK10HCRTR1HCRTR2MAOA | |
| SCHEMBL28819675 | 0.85 | MCHR1 (0.44) | NR1H4MAPK10MAP3K14 | |
| SCHEMBL28819631 | 0.83 | CNR2 (0.45) | NR1H4MAPK10KDM4ECNR2ALOX5AP | |
| SCHEMBL28819698 | 0.83 | PLA2G2A (0.42) | NR1H4CYP11B1CYP11B2CNR2 | |
| SCHEMBL28948676 | 0.82 | NR1H4 (0.40) | NR1H4MAPK10CYP11B1CYP11B2ALOX5AP | |
| SCHEMBL28819665 | 0.81 | POLB (0.40) | NR1H4MAPK10KDM4EKMT2AALOX5AP | |
| Hydrochloric Acid SCHEMBL4213341 | 0.80 | CNR2 (0.49) | KDM4EMAOAMAOBCNR2KMT2A | |
| Hydrochloric Acid SCHEMBL4216436 | 0.80 | MCHR1 (0.46) | CNR2ALOX5AP | |
| Hydrochloric Acid SCHEMBL4213337 | 0.79 | CNR2 (0.48) | KDM4EMAOAMAOBCNR2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110404073-B | Methods and pharmaceutical compositions for treating hepatitis B virus infection | 国家医疗保健研究所 | 2022-08-16 | — | — | CN | disclosed |