Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | PLK1 | P53350 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.36 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.36 |
| ▸ | BRD2 | P25440 | 1/20 | 0.36 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.36 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1100763 | 0.79 | GAA (0.48) | GAAPLK1MTNR1APOLBBRD4 | |
| SCHEMBL8961335 | 0.79 | GAA (0.33) | GAAALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL4281712 | 0.79 | KMT2A (0.38) | GAAALDH1A1PDK2POLBMEN1 | |
| SCHEMBL4049574 | 0.78 | TSHR (0.50) | GAAALDH1A1POLBKMT2ATDP1 | |
| SCHEMBL20448911 | 0.78 | GAA (0.47) | GAAPLK1ALDH1A1MTNR1APOLB | |
| SCHEMBL16951611 | 0.78 | TSHR (0.48) | ALDH1A1POLBSLC6A4SLC6A3KMT2A | |
| SCHEMBL1905760 | 0.77 | ALDH1A1 (0.56) | GAAALDH1A1POLBMEN1KMT2A | |
| SCHEMBL4287348 | 0.77 | GAA (0.47) | GAAPLK1ALDH1A1PDK2POLB | |
| SCHEMBL3093108 | 0.76 | ALDH1A1 (0.48) | GAAALDH1A1POLBHDAC8TDP1 | |
| SCHEMBL3980872 | 0.75 | KDM4E (0.43) | GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104710367-A | Method for synthesizing enzalutamide | UNIV CHINA PHARMA | 2015-06-17 | — | — | CN | claimed |
| CN-117580825-A | Method for preparing non-steroidal antiandrogens | 奎米卡新特缇卡股份有限公司 | 2024-02-20 | — | — | CN | disclosed |
| CN-104710367-A | Method for synthesizing enzalutamide | UNIV CHINA PHARMA | 2015-06-17 | — | — | CN | disclosed |