SCHEMBL4049574

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6318775	0.83	NPSR1 (0.45)	L3MBTL1HPGDALDH1A1NPC1RAB9A
	SCHEMBL28820113	0.78	GAA (0.56)	POLBTDP1ALDH1A1GAAKMT2A
	SCHEMBL4049576	0.78	L3MBTL1 (0.42)	TSHRHTTL3MBTL1POLBTHRB
	SCHEMBL13753123	0.77	NPC1 (0.66)	TSHRHTTL3MBTL1POLBHPGD
	SCHEMBL28467132	0.73	HTT (0.51)	TSHRHTTL3MBTL1POLBHPGD
	SCHEMBL3982704	0.72	TSHR (0.46)	TSHRHTTL3MBTL1POLBHPGD
	SCHEMBL8961335	0.72	GAA (0.33)	HTTHPGDTDP1ALDH1A1GAA
	SCHEMBL4281712	0.72	KMT2A (0.38)	POLBTDP1ALDH1A1GAAKMT2A
	SCHEMBL3982359	0.72	POLB (0.44)	TSHRHTTL3MBTL1POLBHPGD
	Formic Acid SCHEMBL6319995	0.72	NPC1 (0.59)	TSHRHTTL3MBTL1POLBHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.