SCHEMBL28820132

SCHEMBL28820132

CCC(=O)C1CC1c1c(Cl)cccc1Cl

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 2/20 0.39
HTR2A P28223 1/20 0.39
HTR2B P41595 1/20 0.39
ALDH1A1 P00352 2/20 0.37
SLC9A1 P19634 1/20 0.37
KMT2A Q03164 2/20 0.36
MEN1 O00255 1/20 0.36
MAPK1 P28482 1/20 0.36
P2RX7 Q99572 5/20 0.36
AKR1B1 P15121 1/20 0.34
HTR1A P08908 1/20 0.34
HTR7 P34969 1/20 0.34
HTR5A P47898 1/20 0.34
POLB P06746 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29161446 0.82 SLC9A1 (0.56) HTR2CHTR2AHTR2BALDH1A1SLC9A1
SCHEMBL1586594 0.81 ALDH1A1 (0.41) HTR2CHTR2AHTR2BALDH1A1SLC9A1
SCHEMBL6130264 0.81 ALDH1A1 (0.41) HTR2CHTR2AHTR2BALDH1A1SLC9A1
SCHEMBL27700386 0.80 SLC9A1 (0.42) HTR2CHTR2AHTR2BSLC9A1
SCHEMBL15938458 0.79 FFAR1 (0.45) ALDH1A1SLC9A1KMT2AMEN1POLB
SCHEMBL28019284 0.77 HDAC4 (0.40) ALDH1A1
SCHEMBL28004384 0.75 SLC9A1 (0.54) HTR2CHTR2AHTR2BALDH1A1SLC9A1
SCHEMBL13911289 0.74 HDAC4 (0.56) ALDH1A1SLC9A1MAPK1
SCHEMBL14038418 0.74 HDAC4 (0.56) ALDH1A1SLC9A1MAPK1
SCHEMBL6560499 0.74 HDAC4 (0.56) ALDH1A1SLC9A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104822666-A Tetrazolinone compound and use thereof SUMITOMO CHEMICAL CO 2015-08-05 CN disclosed