Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | CMA1 | P23946 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | LPO | P22079 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 2/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1491056 | 0.79 | MEN1 (0.57) | SIGMAR1CMA1MEN1KMT2ALPO | |
| SCHEMBL3605750 | 0.79 | CMA1 (0.51) | SIGMAR1CMA1MEN1KMT2ALPO | |
| SCHEMBL16815257 | 0.77 | KDM4E (0.51) | MEN1KMT2AALDH1A1GAAPKM | |
| SCHEMBL28019832 | 0.74 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1PKMKDM4E | |
| SCHEMBL16815499 | 0.72 | NPBWR1 (0.45) | MEN1KMT2AALDH1A1GAAPKM | |
| SCHEMBL31505857 | 0.72 | NPBWR1 (0.45) | MEN1KMT2AALDH1A1GAAPKM | |
| SCHEMBL28019780 | 0.70 | MEN1 (0.50) | SIGMAR1CMA1MEN1KMT2ALPO | |
| SCHEMBL5792386 | 0.70 | MEN1 (0.59) | SIGMAR1CMA1MEN1KMT2ALPO | |
| SCHEMBL30046633 | 0.70 | MEN1 (0.59) | SIGMAR1CMA1MEN1KMT2ALPO | |
| SCHEMBL1801928 | 0.69 | MEN1 (0.59) | SIGMAR1CMA1MEN1KMT2ALPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104725397-A | Thienopyrimidine derivatives, a process for their preparation and pharmaceutical compositions containing them | SERVIER LAB | 2015-06-24 | — | — | CN | disclosed |