Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.73 |
| ▸ | MEN1 | O00255 | 2/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30249965 | 1.00 | KMT2A (0.73) | KMT2AMEN1ALDH1A1LMNACYP3A4 | |
| SCHEMBL30250037 | 0.87 | GAA (0.54) | KMT2AMEN1ALDH1A1LMNAGAA | |
| SCHEMBL28820231 | 0.87 | GAA (0.54) | KMT2AMEN1ALDH1A1LMNAGAA | |
| SCHEMBL28820240 | 0.85 | KMT2A (0.56) | KMT2AMEN1ALDH1A1LMNACYP3A4 | |
| SCHEMBL29751569 | 0.85 | KMT2A (0.56) | KMT2AMEN1ALDH1A1LMNACYP3A4 | |
| SCHEMBL28713848 | 0.85 | KMT2A (0.74) | KMT2AMEN1ALDH1A1LMNAGAA | |
| SCHEMBL30250150 | 0.84 | KMT2A (0.68) | KMT2AMEN1ALDH1A1LMNACYP3A4 | |
| SCHEMBL28517797 | 0.82 | MEN1 (0.66) | KMT2AMEN1ALDH1A1LMNACYP3A4 | |
| SCHEMBL30776068 | 0.81 | LMNA (0.50) | KMT2AMEN1ALDH1A1LMNAGAA | |
| SCHEMBL3543990 | 0.81 | KMT2A (0.50) | KMT2AMEN1ALDH1A1LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114920616-B | Synthesis process of amidine compound | 南京师范大学 | 2024-04-05 | — | — | CN | disclosed |
| CN-114920616-A | Synthetic process of amidine compound | 南京师范大学 | 2022-08-19 | — | — | CN | disclosed |