Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29751569 | 1.00 | KMT2A (0.56) | KMT2AGAALMNAMEN1ALDH1A1 | |
| SCHEMBL30250037 | 0.98 | GAA (0.54) | KMT2AGAALMNAMEN1ALDH1A1 | |
| SCHEMBL28820231 | 0.98 | GAA (0.54) | KMT2AGAALMNAMEN1ALDH1A1 | |
| SCHEMBL30776068 | 0.85 | LMNA (0.50) | KMT2AGAALMNAMEN1ALDH1A1 | |
| SCHEMBL30249965 | 0.85 | KMT2A (0.73) | KMT2AGAALMNAMEN1ALDH1A1 | |
| SCHEMBL28820221 | 0.85 | KMT2A (0.73) | KMT2AGAALMNAMEN1ALDH1A1 | |
| SCHEMBL30776064 | 0.81 | MEN1 (0.54) | KMT2AMEN1ALDH1A1SMN1; SMN2PKM | |
| SCHEMBL30776037 | 0.80 | LMNA (0.55) | KMT2AGAALMNAMEN1ALDH1A1 | |
| SCHEMBL30776085 | 0.77 | MEN1 (0.50) | KMT2AGAALMNAMEN1ALDH1A1 | |
| SCHEMBL3543990 | 0.76 | KMT2A (0.50) | KMT2AGAALMNAMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114920616-B | Synthesis process of amidine compound | 南京师范大学 | 2024-04-05 | — | — | CN | disclosed |
| CN-114920616-A | Synthetic process of amidine compound | 南京师范大学 | 2022-08-19 | — | — | CN | disclosed |