Butyramide

Butyramide

SCHEMBL28820281

CCCC(N)=O.CCCCNCC

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.58
CYP2C19 P33261 3/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
CYP1A2 P05177 2/20 0.42
SOAT1 P35610 2/20 0.42
FAAH O00519 1/20 0.42
TP53 P04637 1/20 0.42
CYP3A4 P08684 1/20 0.42
GLA P06280 1/20 0.42
ALOX15 P16050 1/20 0.42
CNR1 P21554 1/20 0.40
CASP2 P42575 1/20 0.39
KDM4E B2RXH2 2/20 0.39
GAA P10253 1/20 0.38
EPHX1 P07099 2/20 0.38
HDAC1 Q13547 2/20 0.37
HDAC2 Q92769 2/20 0.37
ALDH1A1 P00352 1/20 0.37
ADH1B P00325 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butyramide SCHEMBL10937056 0.91 TSHR (0.46) TSHRCYP2C19MEN1KMT2ACYP1A2
SCHEMBL3927721 0.87
SCHEMBL25950295 0.85 CYP2C19 (0.52) TSHRCYP2C19MEN1KMT2ACYP1A2
SCHEMBL13469008 0.85 TSHR (0.48) TSHRCYP2C19MEN1KMT2ACYP1A2
SCHEMBL23929280 0.83 CYP2C19 (0.50) TSHRCYP2C19MEN1KMT2ACYP1A2
SCHEMBL1960042 0.83 TSHR (0.46) TSHRCYP2C19MEN1KMT2ACYP1A2
SCHEMBL16306515 0.83 CYP2C19 (0.50) TSHRCYP2C19MEN1KMT2ACYP1A2
SCHEMBL13469009 0.83 TSHR (0.52) TSHRCYP2C19MEN1KMT2ACYP1A2
Diethylamine SCHEMBL28163405 0.82 TP53 (0.48) TSHRCYP2C19MEN1KMT2ACYP1A2
Octadecanoic Acid Amide SCHEMBL28253450 0.81 SOAT1 (0.50) TSHRCYP2C19MEN1KMT2ACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114773289-A Nitrobenzoisothiazole azo compound and application thereof 辽宁庸信达染料化工有限公司 2022-07-22 CN disclosed