Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Salicylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.78 |
| ▸ | HPGD | P15428 | 7/20 | 0.78 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.78 |
| ▸ | CA1 | P00915 | 2/20 | 0.78 |
| ▸ | CA2 | P00918 | 2/20 | 0.78 |
| ▸ | CA12 | O43570 | 1/20 | 0.78 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.78 |
| ▸ | CA4 | P22748 | 1/20 | 0.78 |
| ▸ | CA6 | P23280 | 1/20 | 0.78 |
| ▸ | CA7 | P43166 | 1/20 | 0.78 |
| ▸ | CA9 | Q16790 | 1/20 | 0.78 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.78 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.78 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | G6PD | P11413 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Salicylic Acid SCHEMBL4295686 | 0.98 | KDM4E (0.82) | KDM4EALDH1A1HPGDSMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL31490109 | 0.98 | KDM4E (0.82) | KDM4EALDH1A1HPGDSMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL8176134 | 0.96 | KDM4E (0.78) | KDM4EALDH1A1HPGDSMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL28303438 | 0.92 | KDM4E (0.72) | KDM4EALDH1A1HPGDSMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL973984 | 0.91 | ALDH1A1 (0.95) | KDM4EALDH1A1HPGDSMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL6725453 | 0.89 | KDM4E (0.75) | KDM4EALDH1A1HPGDSMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL9228055 | 0.89 | KDM4E (0.75) | KDM4EALDH1A1HPGDSMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL11514985 | 0.89 | KDM4E (0.75) | KDM4EALDH1A1HPGDSMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL30940555 | 0.89 | KDM4E (0.75) | KDM4EALDH1A1HPGDSMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL9800701 | 0.89 | KDM4E (0.75) | KDM4EALDH1A1HPGDSMN1; SMN2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117342893-A | Salicylic acid iron fertilizer for improving stress resistance of plants and preparation method thereof | 山东省烟台市农业科学研究院(山东省农业科学院烟台市分院) | 2024-01-05 | — | — | CN | disclosed |
| CN-104694341-B | A kind of Radix Et Rhizoma Fagopyri Tatarici five grain yellow wine utilizing daqu of middle temperature to produce and preparation method thereof | 山西农业大学 | 2016-08-24 | — | — | CN | disclosed |
| CN-104694341-A | Tartary buckwheat five-grain yellow rice wine produced through medium temperature Daqu and preparing method thereof | UNIV SHANXI AGRICULTURAL | 2015-06-10 | — | — | CN | disclosed |