Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | SLC16A3 | O15427 | 7/20 | 0.54 |
| ▸ | SLC16A1 | P53985 | 7/20 | 0.54 |
| ▸ | EGFR | P00533 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23605194 | 0.86 | EGFR (0.60) | CYP1A2CYP3A4CYP2C9KDM4ELMNA | |
| SCHEMBL8649661 | 0.84 | CYP1A2 (0.78) | CYP1A2CYP3A4CYP2C9KDM4ELMNA | |
| SCHEMBL3020683 | 0.84 | CYP1A2 (0.58) | CYP1A2CYP3A4CYP2C9KDM4ELMNA | |
| SCHEMBL3020681 | 0.84 | CYP1A2 (0.58) | CYP1A2CYP3A4CYP2C9KDM4ELMNA | |
| SCHEMBL9360940 | 0.84 | CYP1A2 (0.78) | CYP1A2CYP3A4CYP2C9KDM4ELMNA | |
| SCHEMBL20358523 | 0.83 | MIF (0.60) | CYP1A2CYP3A4CYP2C9KDM4ELMNA | |
| SCHEMBL20358526 | 0.83 | MIF (0.60) | CYP1A2CYP3A4CYP2C9KDM4ELMNA | |
| SCHEMBL15428904 | 0.82 | KDM4E (0.68) | CYP1A2CYP3A4CYP2C9KDM4ELMNA | |
| SCHEMBL2459393 | 0.81 | GABRA1 (0.59) | CYP3A4KDM4ELMNAPKMKMT2A | |
| SCHEMBL29394213 | 0.81 | GABRA1 (0.59) | CYP3A4KDM4ELMNAPKMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104726399-A | Application of ethyl p-methoxycinnamate and derivatives thereof to maintaining self-renewal and pluripotency of stem cells | UNIV NORTHEAST NORMAL | 2015-06-24 | — | — | CN | claimed |
| CN-104726399-A | Application of ethyl p-methoxycinnamate and derivatives thereof to maintaining self-renewal and pluripotency of stem cells | UNIV NORTHEAST NORMAL | 2015-06-24 | — | — | CN | disclosed |