Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Butylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 8/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.46 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.46 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butylamine SCHEMBL27467554 | 1.00 | DNM1 (0.50) | DNM1APPTP53MEN1KMT2A | |
| Butylamine SCHEMBL537120 | 1.00 | DNM1 (0.50) | DNM1APPTP53MEN1KMT2A | |
| Butylamine SCHEMBL21981130 | 1.00 | DNM1 (0.50) | DNM1APPTP53MEN1KMT2A | |
| Butylamine SCHEMBL28107057 | 0.97 | TP53 (0.48) | DNM1APPTP53MEN1KMT2A | |
| Butylamine SCHEMBL28986375 | 0.97 | TP53 (0.48) | DNM1APPTP53MEN1KMT2A | |
| Butylamine SCHEMBL28157516 | 0.97 | TP53 (0.48) | DNM1APPTP53MEN1KMT2A | |
| Butylamine SCHEMBL27959281 | 0.97 | TP53 (0.48) | DNM1APPTP53MEN1KMT2A | |
| Butylamine SCHEMBL28172152 | 0.97 | TP53 (0.48) | DNM1APPTP53MEN1KMT2A | |
| Butylamine SCHEMBL27417214 | 0.95 | TP53 (0.46) | DNM1APPTP53MEN1KMT2A | |
| Butylamine SCHEMBL28262920 | 0.95 | TP53 (0.46) | DNM1APPTP53MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 4466 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3275039-B1 | ELECTROLYTES AND METAL HYDRIDE BATTERIES | BASF CORP (US) | 2025-08-27 | — | — | EP | claimed |
| CN-119684090-A | Preparation method of 2,3,5, 6-tetrafluorophenol | 阜新睿光氟化学有限公司 | 2025-03-25 | — | — | CN | claimed |
| CN-114674623-B | Sampling device and sampling method for ultralow-concentration tobacco aroma substances | 湖北中烟工业有限责任公司 | 2024-11-22 | — | — | CN | claimed |
| WO-2024201231-A1 | A PROCESS FOR THE PREPARATION OF ISOXAZOLINE-SUBSTITUTED AMIDE COMPOUNDS AND ITS INTERMEDIATES THEREOF | HIKAL LIMITED (IN) | 2024-10-03 | — | — | WO | claimed |
| CN-118047738-A | Asymmetric synthesis method of (1R, 2S, 3R) -1- ((R) -ethylene oxide-2-yl) -4-pentene-1, 3-diol | 扬州大学 | 2024-05-17 | — | — | CN | claimed |
| CN-113979856-B | Method for recovering tert-butylamine and isooctanoate from potassium clavulanate kettle residual liquid | 国药集团威奇达药业有限公司 | 2024-04-19 | — | — | CN | claimed |
| EP-4294977-A1 | DYE RECYCLING METHODS | Imperial College Innovations Limited (GB) | 2023-12-27 | — | — | EP | claimed |
| CN-116917568-A | Method for recovering dye | 帝国理工学院创新有限公司 | 2023-10-20 | — | — | CN | claimed |
| WO-2023147779-A1 | PREPARATION METHOD OF PYRIDAZINONE DERIVATIVE, AND INTERMEDIATE THEREOF | 四川海思科制药有限公司 | 2023-08-10 | — | — | WO | claimed |
| WO-2023135499-A1 | PROCESS FOR ROXADUSTAT USING NOVEL INTERMEDIATES | OPTIMUS DRUGS PVT LTD (IN) | 2023-07-20 | — | — | WO | claimed |
| CN-1251835-A | Process for synthesizing N-(3'-isopropoxyphenyl)-2-methyl benzoylamine | XINNONG CHEMICAL CO LTD ZHEJIA (CN) | 2000-05-03 | — | — | CN | claimed |
| CN-1041302-C | Synthesis for high purity beta ionone | ZHONGBIAO STANDARD TECHNOLOGY (CN) | 1998-12-23 | — | — | CN | claimed |
| CN-1041198-C | Method for synthesizing 5-[1-hydroxy-2-(isopropylamino)ethyl] aminobenzonitrile | UNIV BEIJING AGRICULT (CN) | 1998-12-16 | — | — | CN | claimed |
| CN-1120535-A | Method for synthesizing 5-[1-hydroxy-2-(isopropylamino)ethyl] aminobenzonitrile | UNIV BEIJING AGRICULT (CN) | 1996-04-17 | — | — | CN | claimed |
| CN-1109462-A | Synthesis for high purity beta ionone | CHONGBIAO STANDARD TECHNOLOGY (CN) | 1995-10-04 | — | — | CN | claimed |
| EP-0413999-A2 | N,N-bis-1,3,5-triazine-6-yl-piperazines and processes for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-02-27 | — | — | EP | claimed |
| EP-0358856-A2 | Novel insecticidal dibenzoyl-tert-butylcarbanonitrile compounds and method for the preparation thereof | AMERICAN CYANAMID COMPANY (US) | 1990-03-21 | — | — | EP | claimed |
| US-4281105-A | Formation of particulate polypyrrolidone | BARNES CARL E | 1981-07-28 | — | — | US | claimed |
| US-4247685-A | Continuous bulk polymerization of 2-pyrrolidone | BARNES CARL E | 1981-01-27 | — | — | US | claimed |
| US-4101273-A | Disperse dyeing with polyglycerine anionic emulsifiers and/or polyaryl polyglycol ethers | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1978-07-18 | — | — | US | claimed |