Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.42 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.39 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | NNMT | P40261 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3712613 | 0.82 | CSNK2A1 (0.59) | PARP1CSNK2A1ALDH1A1HDAC7KDM4E | |
| SCHEMBL26802143 | 0.82 | PARP1 (0.44) | PARP1CSNK2A1MAP2K2MAP2K1ALDH1A1 | |
| SCHEMBL31544787 | 0.82 | CSNK2A1 (0.59) | PARP1CSNK2A1ALDH1A1HDAC7KDM4E | |
| SCHEMBL24311296 | 0.78 | PARP1 (0.44) | PARP1CSNK2A1MAP2K2MAP2K1ALDH1A1 | |
| SCHEMBL6843558 | 0.78 | ALDH1A1 (0.39) | CSNK2A1MAP2K2MAP2K1HPGDALDH1A1 | |
| SCHEMBL1003133 | 0.78 | DGAT1 (0.60) | PARP1CSNK2A1MAP2K2MAP2K1 | |
| SCHEMBL3712612 | 0.78 | CSNK2A1 (0.59) | PARP1CSNK2A1ALDH1A1HDAC7KDM4E | |
| SCHEMBL26805463 | 0.77 | HSP90AB1 (0.46) | PARP1CSNK2A1MAP2K2MAP2K1HPGD | |
| SCHEMBL1804232 | 0.77 | PARP1 (0.47) | PARP1CSNK2A1MAP2K2MAP2K1HPGD | |
| SCHEMBL14800110 | 0.77 | ALDH1A1 (0.48) | CSNK2A1HPGDALDH1A1HTTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103827099-B | Phthalimide-containing benzothiazole derivative or salt thereof and pharmaceutical composition containing same | Liu Hanyangxing (KR) | 2015-09-09 | — | — | CN | disclosed |