Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.47 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.42 |
| ▸ | ST6GAL1 | P15907 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | POLA1 | P09884 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28822175 | 1.00 | NT5E (0.53) | NT5ELMNATHRBMTORMDM2 | |
| SCHEMBL30256934 | 0.87 | NT5E (0.52) | NT5ELMNATHRBMTORMDM2 | |
| SCHEMBL30256877 | 0.87 | NT5E (0.52) | NT5ELMNATHRBMTORMDM2 | |
| SCHEMBL27938161 | 0.87 | NT5E (0.68) | NT5ELMNATHRBMTORMDM2 | |
| SCHEMBL6571375 | 0.87 | NT5E (0.68) | NT5ELMNATHRBMTORMDM2 | |
| SCHEMBL13271029 | 0.82 | LMNA (0.60) | NT5ELMNATHRBMTORMDM2 | |
| SCHEMBL26083563 | 0.81 | NT5E (0.53) | NT5ELMNATHRBMTORMDM2 | |
| SCHEMBL26692867 | 0.81 | NT5E (0.53) | NT5ELMNATHRBMTORMDM2 | |
| SCHEMBL26692863 | 0.81 | NT5E (0.53) | NT5ELMNATHRBMTORMDM2 | |
| SCHEMBL26083706 | 0.81 | NT5E (0.53) | NT5ELMNATHRBMTORMDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105247051-A | Organic compositions for treating EPAS 1-related diseases | NOVARTIS AG | 2016-01-13 | — | — | CN | disclosed |