SCHEMBL6571375

SCHEMBL6571375

Nc1ccn([C@@H]2O[C@H](C(O)P(=O)(O)O)[C@@H](O)[C@H]2O)c(=O)n1

nearest known ligand 0.68

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
NT5E P21589 1/20 0.68
LMNA P02545 1/20 0.58
THRB P10828 1/20 0.58
MTOR P42345 1/20 0.58
MDM2 Q00987 1/20 0.58
NCOA1 Q15788 1/20 0.58
NCOA3 Q9Y6Q9 1/20 0.58
ST6GAL1 P15907 9/20 0.49
P2RY2 P41231 1/20 0.48
TSHR P16473 1/20 0.46
GLA P06280 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27938161 1.00 NT5E (0.68) NT5ELMNATHRBMTORMDM2
Phosphoric Acid SCHEMBL16859831 0.87 NT5E (0.67) NT5ELMNATHRBMTORMDM2
SCHEMBL28822178 0.87 NT5E (0.53) NT5ELMNATHRBMTORMDM2
SCHEMBL28822175 0.87 NT5E (0.53) NT5ELMNATHRBMTORMDM2
SCHEMBL3789915 0.85 NT5E (0.64) NT5ELMNATHRBMTORMDM2
SCHEMBL1763223 0.85 NT5E (0.64) NT5ELMNATHRBMTORMDM2
SCHEMBL1763085 0.85 NT5E (0.64) NT5ELMNATHRBMTORMDM2
SCHEMBL4414290 0.85 NT5E (0.67) NT5ELMNATHRBMTORMDM2
SCHEMBL223209 0.84 NT5E (0.65) NT5ELMNATHRBMTORMDM2
SCHEMBL13134657 0.84 NT5E (0.65) NT5ELMNATHRBMTORMDM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104395480-A Methods and compositions for size-controlled homopolymer tailing of substrate polynucleotides by nucleic acid polymerases SWIFT BIOSCIENCES INC 2015-03-04 CN claimed
EP-4114547-A2 METHODS OF MAKING HYPER-SIALYLATED IMMUNOGLOBULIN Momenta Pharmaceuticals, Inc. (US) 2023-01-11 EP disclosed
WO-2021178682-A2 METHODS OF MAKING HYPER-SIALYLATED IMMUNOGLOBULIN MOMENTA PHARMACEUTICALS, INC. (US) 2021-09-10 WO disclosed
WO-2018115309-A1 PREPARATION OF SUGAR-NUCLEOTIDES NOVO NORDISK A/S (DK) 2018-06-28 WO disclosed
EP-3337488-A1 TREATMENT AND PREVENTION OF NEISSERIA GONORRHOEAE INFECTION USING CMP-ACTIVATED NONULOSONATE ANALOG COMPOUNDS National Research Council of Canada (CA) 2018-06-27 EP disclosed
WO-2017027980-A1 TREATMENT AND PREVENTION OF NEISSERIA GONORRHOEAE INFECTION USING CMP-ACTIVATED NONULOSONATE ANALOG COMPOUNDS NATIONAL RESEARCH COUNCIL CANADA (CA) 2017-02-23 WO disclosed
CN-103338775-B Methods of using human milk oligosaccharides to reduce the incidence of necrotizing enterocolitis in infants, toddlers, or children ABBOTT LABORATORIES (US) 2016-11-30 CN disclosed
CN-106011310-A Method for amplifying and/or detecting nucleic acids, kits and uses of said method 生物梅里埃公司 2016-10-12 CN disclosed
CN-105007758-A Low-buffer nutritional composition and uses thereof MJN US HOLDINGS LLC 2015-10-28 CN disclosed
CN-104395480-A Methods and compositions for size-controlled homopolymer tailing of substrate polynucleotides by nucleic acid polymerases SWIFT BIOSCIENCES INC 2015-03-04 CN disclosed
CN-104126749-A Modulation of growth of bifidobacteria using a combination of oligosaccharides found in human milk NESTEC SA 2014-11-05 CN disclosed
CN-103929980-A Infant formula with high SN-2 palmitate and oligofructose NESTEC SA 2014-07-16 CN disclosed
CN-103338775-A Methods of using human milk oligosaccharides to reduce the incidence of necrotizing enterocolitis in infants, toddlers, or children ABBOTT LAB 2013-10-02 CN disclosed
EP-0640835-B1 Method for determining sugar chain structure TAKARA BIO INC (JP) 2004-04-07 EP disclosed
EP-0640835-A2 Method for determining sugar chain structure TAKARA SHUZO CO. LTD. (JP) 1995-03-01 EP disclosed