Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 14/20 | 0.61 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.61 |
| ▸ | MIF | P14174 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2273470 | 0.98 | P4HTM (0.59) | P4HTMP4HA1MIFKDM4EALDH1A1 | |
| Water SCHEMBL4233061 | 0.98 | P4HTM (0.59) | P4HTMP4HA1MIFKDM4EALDH1A1 | |
| SCHEMBL28429063 | 0.96 | P4HTM (0.57) | P4HTMP4HA1MIFKDM4EALDH1A1 | |
| SCHEMBL9317975 | 0.84 | P4HTM (0.54) | P4HTMP4HA1MIFKDM4EALDH1A1 | |
| SCHEMBL11044314 | 0.83 | P4HTM (0.53) | P4HTMP4HA1MIFKDM4EALDH1A1 | |
| SCHEMBL28225606 | 0.80 | KDM4E (0.44) | P4HTMP4HA1MIFKDM4EALDH1A1 | |
| SCHEMBL6527953 | 0.79 | GRIN2B (0.40) | P4HTMP4HA1MIFKDM4EALDH1A1 | |
| SCHEMBL3163574 | 0.79 | KMT2A (0.55) | P4HTMP4HA1MIFKDM4EALDH1A1 | |
| SCHEMBL1027521 | 0.79 | ALDH1A1 (0.48) | P4HTMP4HA1MIFKDM4EALDH1A1 | |
| SCHEMBL6651827 | 0.78 | P4HTM (0.61) | P4HTMP4HA1MIFKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 692 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025096597-A1 | COMPOSITIONS INCLUDING INHIBITORS OF PTEN EXPRESSION OR ACTIVITY TO PREVENT OR TREAT TYPE 2 DIABETES | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2025-05-08 | — | — | WO | claimed |
| CN-119528806-A | Synthesis method of 5-difluoromethoxy-2-pyridine formaldehyde | 南京琦诺医药科技有限公司 | 2025-02-28 | — | — | CN | claimed |
| CN-119462494-A | Synthesis method of 5-difluoromethoxy-2-pyridine formaldehyde | 南京琦诺医药科技有限公司 | 2025-02-18 | — | — | CN | claimed |
| US-12077680-B2 | Polishing composition, production method of the same, polishing method and a manufacturing method of a semiconductor substrate | FUJIMI INCORPORATED (JP) | 2024-09-03 | — | — | US | claimed |
| CN-118491563-A | Preparation method of metal-organic framework supported iridium-based catalyst and photocatalytic CO2Reduction application | 大连理工大学 | 2024-08-16 | — | — | CN | claimed |
| CN-118126090-A | Iridium complex photosensitizer and preparation method and application thereof | 南京工业大学 | 2024-06-04 | — | — | CN | claimed |
| CN-117364273-B | Preparation method of transverse reinforced PBO (Poly-p-phenylene oxide) fiber | 江苏亨博复合材料有限公司 | 2024-04-26 | — | — | CN | claimed |
| CN-117364273-A | Preparation method of transverse reinforced PBO (Poly-p-phenylene oxide) fiber | 江苏亨博复合材料有限公司 | 2024-01-09 | — | — | CN | claimed |
| WO-2023072104-A1 | METAL-ORGANIC FRAMEWORK MATERIAL AND PREPARATION METHOD THEREFOR | 广东美的白色家电技术创新中心有限公司 | 2023-05-04 | — | — | WO | claimed |
| CN-115050527-A | Railway rod-shaped insulator and manufacturing method thereof | 醴陵华鑫电瓷科技股份有限公司 | 2022-09-13 | — | — | CN | claimed |
| US-20030220521-A1 | Renal-selective prodrugs for control of renal sympathetic nerve activity in the treatment of hypertension | G.D. SEARLE & CO. | 2003-11-27 | — | — | US | claimed |
| WO-2003031930-A2 | A PHOSPHATASE ASSOCIATED WITH METASTASIS | THE JOHNS HOPKINS UNIVERSITY (US) | 2003-04-17 | — | — | WO | claimed |
| WO-1995020390-A1 | USE OF VANADIUM MOLYBDENUM OR TUNGSTEN COMPLEXES FOR CONTROLLING CELLULAR PROLIFERATION | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-08-03 | — | — | WO | claimed |
| EP-0573581-A4 | COMPOSITIONS AND METHODS OF TREATMENT OF SYMPATHETICALLY MAINTAINED PAIN | ARC 1 INC (US) | 1994-06-29 | — | — | EP | claimed |
| EP-0484437-A4 | RENAL-SELECTIVE PRODRUGS FOR THE TREATMENT OF HYPERTENSION | SEARLE & CO (US) | 1994-06-01 | — | — | EP | claimed |
| EP-0573581-A1 | COMPOSITIONS AND METHODS OF TREATMENT OF SYMPATHETICALLY MAINTAINED PAIN | ARC 1, Inc. (US) | 1993-12-15 | — | — | EP | claimed |
| WO-1992014453-A1 | COMPOSITIONS AND METHODS OF TREATMENT OF SYMPATHETICALLY MAINTAINED PAIN | ARC 1, INC. (US) | 1992-09-03 | — | — | WO | claimed |
| EP-0484437-A1 | RENAL-SELECTIVE PRODRUGS FOR THE TREATMENT OF HYPERTENSION | G.D. Searle & Co. (US) | 1992-05-13 | — | — | EP | claimed |
| WO-1992001667-A1 | RENAL-SELECTIVE PRODRUGS FOR CONTROL OF RENAL SYMPATHETIC NERVE ACTIVITY IN THE TREATMENT OF HYPERTENSION | G.D. SEARLE & CO. (US) | 1992-02-06 | — | — | WO | claimed |
| WO-1991001724-A1 | RENAL-SELECTIVE PRODRUGS FOR THE TREATMENT OF HYPERTENSION | G.D. SEARLE & CO. (US) | 1991-02-21 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030220521-A1 | Renal-selective prodrugs for control of renal sympathetic nerve activity in the treatment of hypertension | GLS, APEH, GGH | P4HTM 257/4885P4HA1 167/4885MIF 4264/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.