Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 13/20 | 0.63 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.59 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | UBE2N | P61088 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9054387 | 0.86 | HTR6 (0.67) | HTR6ALKCYP19A1KDM4EUBE2N | |
| SCHEMBL945595 | 0.85 | HTR6 (0.72) | HTR6ALKCYP19A1KDM4EUBE2N | |
| SCHEMBL946516 | 0.83 | HTR6 (0.74) | HTR6ALKCYP19A1KDM4EUBE2N | |
| SCHEMBL28480210 | 0.81 | HTR6 (0.63) | HTR6ALKCYP19A1KDM4EUBE2N | |
| SCHEMBL12700490 | 0.80 | HTR6 (0.72) | HTR6ALKCYP19A1KDM4EUBE2N | |
| SCHEMBL2132873 | 0.80 | HTR6 (0.72) | HTR6ALKCYP19A1KDM4EUBE2N | |
| SCHEMBL29169606 | 0.79 | HTR6 (0.67) | HTR6ALKCYP19A1KDM4EUBE2N | |
| SCHEMBL16375238 | 0.79 | HTR6 (0.79) | HTR6ALKCYP19A1KDM4EUBE2N | |
| SCHEMBL6705984 | 0.79 | HTR6 (0.54) | HTR6ALKCYP19A1KDM4EUBE2N | |
| SCHEMBL31366254 | 0.78 | HTR6 (0.73) | HTR6ALKCYP19A1KDM4EUBE2N |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103420898-B | Diaryl piperidines analog derivative and the application as Mutiple Targets anti-depression drug thereof | SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY (CN) | 2015-10-28 | — | — | CN | disclosed |