Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CIT | O14578 | 2/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 6/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | PRKCB | P05771 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 1/20 | 0.34 |
| ▸ | PRKACA | P17612 | 1/20 | 0.34 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.34 |
| ▸ | MARK3 | P27448 | 1/20 | 0.34 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.34 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.34 |
| ▸ | CLK1 | P49759 | 1/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.34 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.34 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11109935 | 0.86 | TP53 (0.42) | NPC1TP53RAB9ANPSR1DGAT1 | |
| Water SCHEMBL27706790 | 0.82 | TP53 (0.39) | NPC1TP53RAB9ANPSR1DGAT1 | |
| SCHEMBL28035391 | 0.81 | CLK4 (0.34) | CLK4 | |
| SCHEMBL11103424 | 0.77 | MEN1 (0.43) | CLK1GSK3AGSK3BNPC1TP53 | |
| SCHEMBL27687527 | 0.77 | MEN1 (0.45) | ADRB2NPC1TP53RAB9A | |
| SCHEMBL28285879 | 0.73 | MAPT (0.43) | MAP4K4NPC1RAB9A | |
| SCHEMBL11105020 | 0.72 | TP53 (0.42) | ADRB2NPC1TP53RAB9A | |
| SCHEMBL16720037 | 0.72 | MAPT (0.42) | NPC1TP53RAB9ANPSR1 | |
| SCHEMBL468098 | 0.72 | NPC1 (0.42) | NPC1RAB9ANPSR1 | |
| SCHEMBL16457493 | 0.69 | KIF11 (0.47) | GSK3AGSK3BNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105120869-A | Treatment of ocular disorders | KADMON CORP LLC | 2015-12-02 | — | — | CN | disclosed |
| CN-105101996-A | Treatment of ocular disorders | KADMON CORP LLC | 2015-11-25 | — | — | CN | disclosed |