Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | CFD | P00746 | 2/20 | 0.34 |
| ▸ | F11 | P03951 | 1/20 | 0.34 |
| ▸ | TPSB2 | P20231 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | KCNB1 | Q14721 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
| ▸ | RXRG | P48443 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29793825 | 0.82 | CLK4 (0.49) | CLK4DYRK1ACFDF11TPSB2 | |
| SCHEMBL28405109 | 0.82 | CLK4 (0.49) | CLK4DYRK1ACFDF11TPSB2 | |
| SCHEMBL28822652 | 0.81 | CIT (0.39) | CLK4 | |
| SCHEMBL6211007 | 0.76 | RAB9A (0.46) | CLK4DYRK1A | |
| SCHEMBL16719980 | 0.73 | HSD17B1 (0.53) | — | |
| SCHEMBL16719958 | 0.73 | HPGDS (0.40) | CLK4IRAK4 | |
| SCHEMBL11105129 | 0.73 | KIF11 (0.50) | CLK4DYRK1ARXRARXRB | |
| SCHEMBL28035390 | 0.72 | FYN (0.46) | CLK4IRAK4 | |
| SCHEMBL468098 | 0.71 | NPC1 (0.42) | — | |
| SCHEMBL11109935 | 0.71 | TP53 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105120869-A | Treatment of ocular disorders | KADMON CORP LLC | 2015-12-02 | — | — | CN | disclosed |
| CN-105101996-A | Treatment of ocular disorders | KADMON CORP LLC | 2015-11-25 | — | — | CN | disclosed |