Phenol

Phenol

SCHEMBL28822751

Cc1ccccc1Oc1ccccc1O.Oc1ccccc1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.47
CA1 P00915 2/20 0.47
CA2 P00918 2/20 0.47
TP53 P04637 1/20 0.47
MEN1 O00255 1/20 0.46
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
KMT2A Q03164 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
CA12 O43570 1/20 0.42
GLA P06280 1/20 0.42
CA3 P07451 1/20 0.42
CA4 P22748 1/20 0.42
CA9 Q16790 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
CA14 Q9ULX7 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2C19 P33261 1/20 0.42
LMNA P02545 2/20 0.40
ALOX15 P16050 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL981248 0.92 TSHR (0.54) TSHRCA1CA2TP53MEN1
Orthocresol SCHEMBL9667300 0.84 TSHR (0.52) TSHRCA1CA2TP53MEN1
SCHEMBL2865455 0.81 MAOB (0.53) TSHRCA1CA2TP53MEN1
SCHEMBL27854468 0.80 TRPA1 (0.58) TSHRCA1CA2TP53MEN1
SCHEMBL31093955 0.78 TRPA1 (0.56) TSHRCA1CA2TP53MEN1
SCHEMBL981349 0.78 TRPA1 (0.56) TSHRCA1CA2TP53MEN1
SCHEMBL29446988 0.78 CA2 (0.62) TSHRCA1CA2TP53NPC1
SCHEMBL29637724 0.78 TSHR (0.65) TSHRCA1CA2MEN1NPC1
SCHEMBL127000 0.78 TSHR (0.65) TSHRCA1CA2MEN1NPC1
SCHEMBL18197 0.78 CA2 (0.62) TSHRCA1CA2TP53NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105102422-A Method for producing isocyanate ASAHI KASEI CHEMICALS CORP 2015-11-25 CN disclosed