Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 11/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | DHODH | Q02127 | 2/20 | 0.43 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | TYK2 | P29597 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29789879 | 0.79 | WDR5 (0.56) | WDR5JAK2JAK1TYK2JAK3 | |
| SCHEMBL29789664 | 0.77 | CHKA (0.56) | WDR5KMT2APSMB8AOC3HRH3 | |
| SCHEMBL17921462 | 0.72 | DHODH (0.56) | WDR5DHODHPSMB8PARP1JAK1 | |
| SCHEMBL25939550 | 0.71 | DHODH (0.51) | WDR5DHODHPSMB8PARP1JAK1 | |
| SCHEMBL17921460 | 0.71 | DHODH (0.51) | WDR5DHODHPSMB8PARP1CNR2 | |
| SCHEMBL28247345 | 0.71 | HTT (0.55) | DHODHHRH3 | |
| SCHEMBL29789743 | 0.71 | WDR5 (0.62) | WDR5 | |
| SCHEMBL20896682 | 0.71 | WDR5 (0.62) | WDR5 | |
| SCHEMBL21905265 | 0.70 | DHODH (0.84) | DHODHPARP1 | |
| SCHEMBL23645631 | 0.70 | DHODH (0.50) | WDR5DHODHPSMB8AOC3PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109195965-B | Inhibitors of WDR5 protein-protein binding | 普罗佩纶治疗公司 | 2022-07-26 | — | — | CN | disclosed |