Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | CCR1 | P32246 | 3/20 | 0.44 |
| ▸ | CCR5 | P51681 | 3/20 | 0.44 |
| ▸ | CCR8 | P51685 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | MMP2 | P08253 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12023644 | 0.81 | CCR1 (0.57) | LMNAKDM4ECCR1CCR5CCR8 | |
| SCHEMBL170181 | 0.80 | LMNA (0.61) | LMNAKDM4ECCR1CCR5CCR8 | |
| Phenylboronic Acid SCHEMBL28888633 | 0.79 | LMNA (0.70) | LMNAKDM4ECCR1CCR5CCR8 | |
| SCHEMBL12853122 | 0.76 | LMNA (0.61) | LMNAKDM4ECCR1CCR5CCR8 | |
| SCHEMBL12853125 | 0.76 | LMNA (0.61) | LMNAKDM4ECCR1CCR5CCR8 | |
| SCHEMBL29420010 | 0.76 | CA1 (0.52) | LMNAKDM4ECCR1CCR5CCR8 | |
| SCHEMBL18774829 | 0.76 | CCR1 (0.65) | LMNAKDM4ECCR1CCR5CCR8 | |
| SCHEMBL28719166 | 0.76 | CA1 (0.52) | LMNAKDM4ECCR1CCR5CCR8 | |
| SCHEMBL7555958 | 0.76 | LMNA (0.56) | LMNAKDM4ECCR1CCR5CCR8 | |
| SCHEMBL11401809 | 0.75 | LMNA (0.54) | LMNAKDM4ECCR1CCR5CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110015952-B | Diaryl methane compound and preparation method and application thereof | 北京大学深圳研究生院 | 2022-08-19 | — | — | CN | disclosed |