Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Docosanol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.56 |
| ▸ | PPARG | P37231 | 7/20 | 0.56 |
| ▸ | PPARD | Q03181 | 7/20 | 0.56 |
| ▸ | PPARA | Q07869 | 7/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.56 |
| ▸ | TLR2 | O60603 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | FABP4 | P15090 | 2/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.56 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.56 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.56 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dodecanol SCHEMBL23364909 | 1.00 | TSHR (0.68) | TSHRALDH1A1LMNAHSD17B10MEN1 | |
| Myristyl Alcohol SCHEMBL29391910 | 0.97 | TSHR (0.65) | TSHRALDH1A1LMNAHSD17B10MEN1 | |
| Tetradecane SCHEMBL4332025 | 0.92 | GPR84 (0.65) | TSHRALDH1A1LMNAHSD17B10MEN1 | |
| Decane SCHEMBL4332022 | 0.92 | GPR84 (0.65) | TSHRALDH1A1LMNAHSD17B10MEN1 | |
| Heptane SCHEMBL28087513 | 0.92 | GPR84 (0.65) | TSHRALDH1A1LMNAHSD17B10MEN1 | |
| Myristyl Alcohol SCHEMBL16212814 | 0.90 | TSHR (0.68) | TSHRALDH1A1LMNAHSD17B10MEN1 | |
| Dodecanol SCHEMBL27696059 | 0.90 | TSHR (0.68) | TSHRALDH1A1LMNAHSD17B10MEN1 | |
| Myristyl Alcohol SCHEMBL28353736 | 0.90 | TSHR (0.68) | TSHRALDH1A1LMNAHSD17B10MEN1 | |
| Cetyl Alcohol SCHEMBL27622135 | 0.90 | TSHR (0.68) | TSHRALDH1A1LMNAHSD17B10MEN1 | |
| Cetostearyl Alcohol SCHEMBL27505872 | 0.90 | TSHR (0.68) | TSHRALDH1A1LMNAHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113387921-B | Method for synthesizing glycolide | 华东理工大学 | 2022-08-19 | — | — | CN | disclosed |