SCHEMBL2882328

SCHEMBL2882328

O=C(Oc1cccc(F)c1OC(=O)c1ccc(Cl)cc1)c1ccc(Cl)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 1/20 0.62
SLC2A4 P14672 1/20 0.62
KMT2A Q03164 11/20 0.51
LMNA P02545 2/20 0.51
NPC1 O15118 1/20 0.51
NR1I2 O75469 1/20 0.51
TP53 P04637 1/20 0.51
AHR P35869 1/20 0.51
RAB9A P51151 1/20 0.51
TAAR1 Q96RJ0 1/20 0.51
ALOX15 P16050 2/20 0.42
MAPT P10636 5/20 0.42
MEN1 O00255 3/20 0.40
ALDH1A1 P00352 2/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2C9 P11712 1/20 0.40
HPGD P15428 1/20 0.40
CYP2C19 P33261 1/20 0.40
SMN1; SMN2 Q16637 4/20 0.40
GAA P10253 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2886267 0.85 SLC2A1 (0.72) SLC2A1SLC2A4KMT2ALMNAALOX15
SCHEMBL6358969 0.78 SLC2A1 (0.81) SLC2A1SLC2A4KMT2AALOX15MAPT
SCHEMBL19183300 0.77 SLC2A1 (1.00) SLC2A1SLC2A4KMT2ANPC1RAB9A
SCHEMBL30465014 0.77 SLC2A1 (1.00) SLC2A1SLC2A4KMT2ANPC1RAB9A
SCHEMBL28796940 0.76 KMT2A (0.49) KMT2ALMNANPC1NR1I2TP53
SCHEMBL10180647 0.74 SLC2A1 (0.57) SLC2A1SLC2A4KMT2ALMNATP53
SCHEMBL10091253 0.74 ESR1 (0.55) SLC2A1SLC2A4KMT2ANPC1RAB9A
SCHEMBL10824225 0.73 KMT2A (0.47) KMT2ALMNANPC1NR1I2TP53
SCHEMBL11089698 0.73 KMT2A (0.60) KMT2ALMNANPC1NR1I2TP53
SCHEMBL2838570 0.73 KMT2A (0.52) SLC2A1SLC2A4KMT2ALMNANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9464144-B2 Enhanced procatalyst composition and process W. R. Grace & Co.—Conn. (US) 2016-10-11 US claimed
US-9464144-B2 Enhanced procatalyst composition and process W. R. Grace & Co.—Conn. (US) 2016-10-11 US disclosed
EP-2373701-B1 ENHANCED PROCATALYST COMPOSITION AND PROCESS GRACE W R & CO (US) 2016-03-09 EP disclosed
US-20140274668-A1 ENHANCED PROCATALYST COMPOSITION AND PROCESS W. R. GRACE & CO.-CONN. (US) 2014-09-18 US disclosed
US-8778826-B2 Enhanced procatalyst composition and process W. R. GRACE & CO.-CONN. (US) 2014-07-15 US disclosed
US-20100173769-A1 Enhanced Procatalyst Composition and Process W. R. GRACE & CO.-CONN. 2010-07-08 US disclosed