Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.72 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | ESR1 | P03372 | 2/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | JAK2 | O60674 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | METAP2 | P50579 | 1/20 | 0.49 |
| ▸ | METAP1 | P53582 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | TOP1 | P11387 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10180647 | 0.89 | SLC2A1 (0.57) | SLC2A1SLC2A4KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL3826754 | 0.87 | KMT2A (0.66) | SLC2A1SLC2A4KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL1323923 | 0.85 | KMT2A (0.63) | SLC2A1SLC2A4KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL2882328 | 0.85 | SLC2A1 (0.62) | SLC2A1SLC2A4KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL10180669 | 0.84 | KMT2A (0.58) | SLC2A1SLC2A4KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL19183300 | 0.84 | SLC2A1 (1.00) | SLC2A1SLC2A4KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL30465014 | 0.84 | SLC2A1 (1.00) | SLC2A1SLC2A4KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL6358969 | 0.82 | SLC2A1 (0.81) | SLC2A1SLC2A4KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL15283463 | 0.79 | KMT2A (0.56) | SLC2A1SLC2A4KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL6939316 | 0.79 | KMT2A (0.56) | SLC2A1SLC2A4KMT2AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9464144-B2 | Enhanced procatalyst composition and process | W. R. Grace & Co.—Conn. (US) | 2016-10-11 | — | — | US | disclosed |
| US-9464144-B2 | Enhanced procatalyst composition and process | W. R. Grace & Co.—Conn. (US) | 2016-10-11 | — | — | US | disclosed |
| EP-2373701-B1 | ENHANCED PROCATALYST COMPOSITION AND PROCESS | GRACE W R & CO (US) | 2016-03-09 | — | — | EP | disclosed |
| US-20140274668-A1 | ENHANCED PROCATALYST COMPOSITION AND PROCESS | W. R. GRACE & CO.-CONN. (US) | 2014-09-18 | — | — | US | disclosed |
| US-20140274668-A1 | ENHANCED PROCATALYST COMPOSITION AND PROCESS | W. R. GRACE & CO.-CONN. (US) | 2014-09-18 | — | — | US | disclosed |
| US-8778826-B2 | Enhanced procatalyst composition and process | W. R. GRACE & CO.-CONN. (US) | 2014-07-15 | — | — | US | disclosed |
| US-8778826-B2 | Enhanced procatalyst composition and process | W. R. GRACE & CO.-CONN. (US) | 2014-07-15 | — | — | US | disclosed |
| US-8604235-B2 | Production of substituted phenylene aromatic diesters and compositions | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-12-10 | — | — | US | disclosed |
| US-20100204506-A1 | Production of Substituted Phenylene Aromatic Diesters and Compositions | W. R. GRACE & CO.-CONN. | 2010-08-12 | — | — | US | disclosed |
| US-20100204506-A1 | Production of Substituted Phenylene Aromatic Diesters and Compositions | W. R. GRACE & CO.-CONN. | 2010-08-12 | — | — | US | disclosed |
| US-20100204506-A1 | Production of Substituted Phenylene Aromatic Diesters and Compositions | W. R. GRACE & CO.-CONN. | 2010-08-12 | — | — | US | disclosed |
| US-20100173769-A1 | Enhanced Procatalyst Composition and Process | W. R. GRACE & CO.-CONN. | 2010-07-08 | — | — | US | disclosed |
| US-20100173769-A1 | Enhanced Procatalyst Composition and Process | W. R. GRACE & CO.-CONN. | 2010-07-08 | — | — | US | disclosed |
| WO-2010078503-A1 | ENHANCED PROCATALYST COMPOSITION AND PROCESS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2010-07-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100204506-A1 | Production of Substituted Phenylene Aromatic Diesters and Compositions | PAH, DDC, DDT | SLC2A1 4553/4885SLC2A4 2908/4885KMT2A 1611/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.