Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGBL2 | Q5U5Z8 | 2/20 | 0.46 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPKAPK2 | P49137 | 3/20 | 0.34 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.34 |
| ▸ | GABRE | P78334 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28944518 | 0.81 | MAPKAPK2 (0.46) | AGBL2GABRR1KDM4EMAPKAPK2GABRP | |
| SCHEMBL1807187 | 0.80 | MAPKAPK2 (0.33) | KDM4EMAPKAPK2ALDH1A1ALOX15KMT2A | |
| SCHEMBL21193052 | 0.75 | KDM4E (0.47) | KDM4EPOLBSMN1; SMN2MAPKAPK2ALDH1A1 | |
| SCHEMBL30784909 | 0.75 | KDM4E (0.47) | KDM4EPOLBSMN1; SMN2MAPKAPK2ALDH1A1 | |
| SCHEMBL27870869 | 0.74 | AGBL2 (0.47) | AGBL2GABRR1KDM4EPOLBSMN1; SMN2 | |
| SCHEMBL27887048 | 0.74 | GABRR1 (0.50) | AGBL2GABRR1KDM4EPOLBSMN1; SMN2 | |
| SCHEMBL1807189 | 0.73 | MAPKAPK2 (0.36) | KDM4EPOLBSMN1; SMN2MAPKAPK2ALDH1A1 | |
| SCHEMBL29364954 | 0.73 | KDM4E (0.34) | KDM4EMAPKAPK2ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL28504409 | 0.73 | GABRR1 (0.44) | AGBL2GABRR1KDM4EPOLBSMN1; SMN2 | |
| SCHEMBL160005 | 0.73 | KDM4E (0.34) | KDM4EMAPKAPK2ALDH1A1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102770435-B | Pyrazolopyrimidines and the purposes as PDE10 inhibitor thereof | MITSUBISHI TANABE PHARMA CORP. (JP) | 2015-11-25 | — | — | CN | disclosed |