SCHEMBL160005

SCHEMBL160005

CCc1nc(C)cnc1C

nearest known ligand 0.34

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.34
ALDH1A1 P00352 2/20 0.34
S1PR4 O95977 1/20 0.34
KDM5B Q9UGL1 2/20 0.33
TSHR P16473 1/20 0.32
ATM Q13315 2/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
JAK3 P52333 1/20 0.32
USP2 O75604 1/20 0.31
HPGD P15428 1/20 0.31
HSD17B10 Q99714 1/20 0.31
GAA P10253 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
MAPKAPK2 P49137 2/20 0.30
MEN1 O00255 1/20 0.30
TP53 P04637 1/20 0.30
KMT2A Q03164 1/20 0.30
CRHR1 P34998 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29364954 1.00 KDM4E (0.34) KDM4EALDH1A1S1PR4KDM5BTSHR
SCHEMBL29350484 0.92 JAK3 (0.32) KDM4EALDH1A1S1PR4KDM5BJAK3
SCHEMBL28250244 0.85 S1PR4 (0.31) S1PR4
SCHEMBL29832120 0.83 KDM4E (0.35) KDM4EALDH1A1S1PR4KDM5BTSHR
SCHEMBL756047 0.83 KDM4E (0.35) KDM4EALDH1A1S1PR4KDM5BTSHR
SCHEMBL30689655 0.82 HSP90AA1 (0.36) KDM4EALDH1A1JAK3MAPKAPK2
SCHEMBL10307332 0.82 HSP90AA1 (0.36) KDM4EALDH1A1JAK3MAPKAPK2
SCHEMBL29666109 0.81 JAK3 (0.35) KDM4EALDH1A1S1PR4KDM5BJAK3
SCHEMBL108874 0.81 JAK3 (0.35) KDM4EALDH1A1S1PR4KDM5BJAK3
SCHEMBL293166 0.79 MAPKAPK2 (0.34) S1PR4MAPKAPK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1798 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4731020-A1 LOW SUGAR-BASED FOOD COMPOSITIONS WITH ROASTED INGREDIENT Société des Produits Nestlé S.A. (CH) 2026-04-29 EP claimed
US-20260096574-A1 CHOCOLATE REPLICAS PRODUCED FROM INDIVIDUAL COMPONENTS VOYAGE FOODS INC (US) 2026-04-09 US claimed
EP-4369947-B1 FLAVOR ENHANCER FOR PROVIDING ROASTED CHICKEN FLAVOR GIVAUDAN SA (CH) 2026-04-01 EP claimed
US-12568998-B2 Flavouring composition with balanced taste profile SYMRISE AG (DE) 2026-03-10 US claimed
US-20260007144-A1 CHOCOLATE REPLICAS PRODUCED FROM INDIVIDUAL COMPONENTS VOYAGE FOODS INC (US) 2026-01-08 US claimed
EP-4672982-A1 PROCESS FOR PREPARING A FLAVOR COMPOSITION Firmenich SA (CH) 2026-01-07 EP claimed
EP-4518663-B1 RODENT CONTROL BY ALTERNATE OLFACTORY SIMULATION MELCHIOR MATERIAL & LIFE SCIENCE FRANCE (FR) 2025-12-17 EP claimed
US-20250344730-A1 LOW SUGAR-BASED FOOD COMPOSITIONS WITH ROASTED INGREDIENT NESTLE SA (CH) 2025-11-13 US claimed
US-20250331538-A1 MALLEABLE CONSUMABLE PRODUCT FOR ANIMALS AND METHODS OF MANUFACTURE THEREOF BIG HEART PET, INC. (US) 2025-10-30 US claimed
EP-4630411-A1 FORMULATION FOR AROMATIZING A FOOD PRODUCT Döhler GmbH (DE) 2025-10-15 EP claimed
WO-2003101216-A2 COFFEE AROMA HAVING AN IMPROVED STABILITY SYMRISE GMBH & CO. KG (DE) 2003-12-11 WO claimed
EP-0413368-B1 Bread aroma, production thereof, and use of the same for the aromatisation of foodstuffs and delicacies THURN & TAXIS BRAUEREI (DE) 1994-08-17 EP claimed
EP-0413368-A1 Bread aroma, production thereof, and use of the same for the aromatisation of foodstuffs and delicacies FÜRSTLICHE BRAUEREI THURN UND TAXIS REGENSBURG GMBH (DE) 1991-02-20 EP claimed
US-4871848-A OIL, GAS WELLS CORROSION INHIBITORS THE DOW CHEMICAL COMPANY (US) 1989-10-03 US claimed
US-4740320-A REACTION OF NITROGEN-CONTAINING AROMATIC HETEROCYCLIC COMPONENT, KETONE OR ALDEHYDE, AMINE OR POLYAMINE THE DOW CHEMICAL COMPANY (US) 1988-04-26 US claimed
US-4725373-A CORROSION RESISTANCE FOR METAL TOOLS AND EQUIPMENT USED IN OIL AND GAS WELLS THE DOW CHEMICAL COMPANY (US) 1988-02-16 US claimed
US-4578439-A Styryl pyridine cyanates, styryl pyrazine cyanates and polymers thereof THE DOW CHEMICAL COMPANY (US) 1986-03-25 US claimed
US-4179526-A 2-((METHYLTHIO)METHYL)-3-PHENYL-2-PROPENAL INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1979-12-18 US claimed
US-4156029-A Alpha-substituted alkylidene methionals and uses thereof in foodstuffs and flavors for foodstuffs INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1979-05-22 US claimed
US-4064279-A Alpha-substituted alkylidene methionals and uses thereof in foodstuffs and flavors for foodstuffs INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1977-12-20 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12568998-B2 Flavouring composition with balanced taste profile TAS2R20, TAS2R50, TAS2R40 KDM4E 4345/4885ALDH1A1 1337/4885S1PR4 1662/4885
US-20260007144-A1 CHOCOLATE REPLICAS PRODUCED FROM INDIVIDUAL COMPONENTS HAAO, PTGES2, PTGES KDM4E 331/4885ALDH1A1 74/4885S1PR4 2041/4885
US-20260096574-A1 CHOCOLATE REPLICAS PRODUCED FROM INDIVIDUAL COMPONENTS HAAO, HTR6, SCD KDM4E 95/4885ALDH1A1 492/4885S1PR4 2681/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.