SCHEMBL288237

SCHEMBL288237

Nc1ncnc2c1ncn2Cc1cccc(O)c1

nearest known ligand 0.71

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 7/20 0.71
PI4KA P42356 2/20 0.71
PI4K2B Q8TCG2 2/20 0.71
PI4K2A Q9BTU6 2/20 0.71
PI4KB Q9UBF8 2/20 0.71
SLC29A1 Q99808 1/20 0.54
HPGD P15428 1/20 0.53
MAPK1 P28482 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
ADORA1 P30542 4/20 0.52
EGFR P00533 1/20 0.50
DAPK1 P53355 1/20 0.49
ALDH1A1 P00352 1/20 0.49
ADORA2B P29275 1/20 0.49
PIK3CD O00329 1/20 0.48
AHCY P23526 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL448640 0.84 ADORA2A (0.71) ADORA2API4KAPI4K2BPI4K2API4KB
SCHEMBL11015789 0.84 ADORA2A (0.71) ADORA2API4KAPI4K2BPI4K2API4KB
9-Benzyl-9H-Adenine SCHEMBL104932 0.83 ADORA2A (1.00) ADORA2API4KAPI4K2BPI4K2API4KB
SCHEMBL31139304 0.81 PDE4A (0.55) ADORA2API4KAPI4K2BPI4K2API4KB
SCHEMBL6381371 0.80 ADORA2A (0.63) ADORA2API4KAPI4K2BPI4K2API4KB
SCHEMBL11811272 0.77 ADORA2A (0.64) ADORA2API4KAPI4K2BPI4K2API4KB
SCHEMBL13268696 0.77 ADORA2A (0.56) ADORA2API4KAPI4K2BPI4K2API4KB
SCHEMBL21121702 0.76 ADORA2A (0.40) ADORA2API4KAPI4K2BPI4K2API4KB
SCHEMBL22533530 0.76 ADORA2A (0.71) ADORA2API4KAPI4K2BPI4K2API4KB
SCHEMBL21788552 0.76 ADORA2A (0.76) ADORA2API4KAPI4K2BPI4K2API4KB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11751573-B2 Seaweed composition PORT LOUIS BERNARD (SC) 2023-09-12 US disclosed
US-20200337315-A1 SEAWEED COMPOSITION PORT LOUIS BERNARD (SC) 2020-10-29 US disclosed
US-20120137390-A1 MATERIALS AND METHODS FOR REGENERATION AND TRANSFORMATION OF TREES ARBORGEN INC. 2012-05-31 US disclosed
EP-2427047-A2 MATERIALS AND METHODS FOR REGENERATION AND TRANSFORMATION OF TREES ArborGen Inc. (US) 2012-03-14 EP disclosed
WO-2010129737-A2 MATERIALS AND METHODS FOR REGENERATION AND TRANSFORMATION OF TREES ARBORGEN, LLC (US) 2010-11-11 WO disclosed