Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 9/20 | 0.63 |
| ▸ | PI4KA | P42356 | 3/20 | 0.63 |
| ▸ | PI4K2B | Q8TCG2 | 3/20 | 0.63 |
| ▸ | PI4K2A | Q9BTU6 | 3/20 | 0.63 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.63 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.56 |
| ▸ | AHCY | P23526 | 8/20 | 0.54 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL288237 | 0.80 | ADORA2A (0.71) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| 9-Benzyl-9H-Adenine SCHEMBL104932 | 0.78 | ADORA2A (1.00) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL13268696 | 0.77 | ADORA2A (0.56) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL21788552 | 0.77 | ADORA2A (0.76) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL3395858 | 0.76 | HSP90AA1 (0.62) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL22533851 | 0.75 | ADORA2A (0.74) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL6659204 | 0.75 | ADORA2A (0.74) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL22533785 | 0.75 | ADORA2A (0.68) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL11811272 | 0.75 | ADORA2A (0.64) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL29424732 | 0.75 | ADORA2A (0.68) | ADORA2API4KAPI4K2BPI4K2API4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501850-A2 | NUCLEOSIDE DERIVATIVES FOR TREATING HEPATITIS C VIRUS INFECTION | GENELABS TECHNOLOGIES, INC. (US) | 2005-02-02 | — | — | EP | claimed |
| WO-2003093290-A2 | NUCLEOSIDE DERIVATIVES FOR TREATING HEPATITIS C VIRUS INFECTION | GENELABS TECHNOLOGIES, INC. (US) | 2003-11-13 | — | — | WO | claimed |