Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 6/20 | 0.58 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.58 |
| ▸ | CMA1 | P23946 | 1/20 | 0.43 |
| ▸ | AHR | P35869 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.37 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30430557 | 1.00 | PNMT (0.58) | PNMTASIC3CMA1AHRPARP10 | |
| SCHEMBL3141361 | 0.86 | PNMT (0.56) | PNMTASIC3CMA1AHRPARP10 | |
| SCHEMBL1612916 | 0.79 | PNMT (0.57) | PNMTASIC3CMA1AHRPARP10 | |
| SCHEMBL29414378 | 0.79 | PNMT (0.57) | PNMTASIC3CMA1AHRPARP10 | |
| SCHEMBL3141037 | 0.78 | PARP1 (0.40) | PNMTASIC3PARP10PARP1HTR2A | |
| SCHEMBL2062026 | 0.78 | KDM4E (0.41) | PNMTASIC3HTR2AHTR2CHTR2B | |
| SCHEMBL6618092 | 0.78 | PNMT (0.56) | PNMTASIC3CMA1AHRPARP10 | |
| SCHEMBL9055504 | 0.78 | ALDH1A1 (0.44) | PNMTASIC3PARP10PARP1ADRA2A | |
| Hydrochloric Acid SCHEMBL595700 | 0.78 | PNMT (0.55) | PNMTASIC3CMA1AHRPARP10 | |
| SCHEMBL384362 | 0.76 | KDM4E (0.48) | PNMTASIC3CMA1AHRPARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114929691-A | Bicyclic compounds and uses thereof | 爱思开生物制药株式会社 | 2022-08-19 | — | — | CN | disclosed |