Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.46 |
| ▸ | CASP3 | P42574 | 3/20 | 0.46 |
| ▸ | TLR2 | O60603 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15669323 | 1.00 | KMT2A (0.68) | KMT2AEPHX2CASP3TLR2 | |
| SCHEMBL7752815 | 0.93 | KMT2A (0.67) | KMT2ACASP3TLR2 | |
| SCHEMBL31546963 | 0.92 | KMT2A (0.57) | KMT2AEPHX2CASP3TLR2 | |
| SCHEMBL15669319 | 0.92 | KMT2A (0.62) | KMT2ACASP3TLR2 | |
| SCHEMBL31720110 | 0.86 | KMT2A (0.52) | KMT2ACASP3TLR2 | |
| SCHEMBL29697708 | 0.85 | KMT2A (0.51) | KMT2AEPHX2CASP3TLR2 | |
| SCHEMBL29603695 | 0.85 | KMT2A (0.51) | KMT2AEPHX2CASP3TLR2 | |
| SCHEMBL27637562 | 0.85 | KMT2A (0.51) | KMT2AEPHX2CASP3TLR2 | |
| SCHEMBL8902890 | 0.85 | KMT2A (0.51) | KMT2AEPHX2CASP3TLR2 | |
| SCHEMBL15669252 | 0.85 | KMT2A (0.64) | KMT2AEPHX2CASP3TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105121421-A | Spliceostatin analogs | PFIZER | 2015-12-02 | — | — | CN | disclosed |