Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | CASP3 | P42574 | 4/20 | 0.50 |
| ▸ | MDM4 | O15151 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | TLR2 | O60603 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29697708 | 1.00 | KMT2A (0.51) | KMT2ACASP3MDM4TP53EPHX2 | |
| SCHEMBL27637562 | 1.00 | KMT2A (0.51) | KMT2ACASP3MDM4TP53EPHX2 | |
| SCHEMBL29603695 | 1.00 | KMT2A (0.51) | KMT2ACASP3MDM4TP53EPHX2 | |
| SCHEMBL29376420 | 0.92 | KMT2A (0.50) | KMT2ACASP3MDM4TP53EPHX2 | |
| SCHEMBL24580473 | 0.91 | KMT2A (0.49) | KMT2ACASP3EPHX2 | |
| SCHEMBL30560164 | 0.91 | CASP3 (0.53) | KMT2ACASP3MDM4TP53EPHX2 | |
| SCHEMBL31546963 | 0.89 | KMT2A (0.57) | KMT2ACASP3MDM4TP53EPHX2 | |
| SCHEMBL18429471 | 0.88 | KMT2A (0.53) | KMT2ACASP3MDM4TP53EPHX2 | |
| SCHEMBL1668211 | 0.88 | KMT2A (0.53) | KMT2ACASP3MDM4TP53EPHX2 | |
| SCHEMBL30028151 | 0.88 | KMT2A (0.53) | KMT2ACASP3MDM4TP53EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022138891-A1 | METHOD FOR PRODUCING PEPTIDE COMPOUND CONTAINING N-SUBSTITUTED-AMINO ACID RESIDUE | 中外製薬株式会社 | 2022-06-30 | — | — | WO | disclosed |
| US-5639859-A | Carboxylate protective groups, a process for their preparation, their coupling to a functional group, and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-06-17 | — | — | US | disclosed |
| US-5439806-A | Carboxylate protective groups, a process for their preparation, their coupling to a functional group, and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-08-08 | — | — | US | disclosed |