Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | TLR2 | O60603 | 2/20 | 0.45 |
| ▸ | CASP3 | P42574 | 2/20 | 0.42 |
| ▸ | MDM4 | O15151 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28823765 | 0.93 | KMT2A (0.68) | KMT2ATLR2CASP3 | |
| SCHEMBL15669323 | 0.93 | KMT2A (0.68) | KMT2ATLR2CASP3 | |
| SCHEMBL15669319 | 0.87 | KMT2A (0.62) | KMT2ATLR2CASP3 | |
| SCHEMBL574816 | 0.86 | KMT2A (0.64) | KMT2ATLR2CASP3 | |
| SCHEMBL29376420 | 0.86 | KMT2A (0.50) | KMT2ATLR2CASP3MDM4TP53 | |
| SCHEMBL31546963 | 0.85 | KMT2A (0.57) | KMT2ATLR2CASP3MDM4TP53 | |
| SCHEMBL13295942 | 0.83 | KMT2A (0.64) | KMT2ATLR2CASP3 | |
| SCHEMBL1486209 | 0.83 | CASP3 (0.54) | KMT2ACASP3MDM4TP53 | |
| SCHEMBL2551441 | 0.83 | CASP3 (0.54) | KMT2ACASP3MDM4TP53 | |
| SCHEMBL119400 | 0.83 | CASP3 (0.54) | KMT2ACASP3MDM4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1068222-A1 | RADIOPHARMACEUTICALS FOR IMAGING INFECTION AND INFLAMMATION AND FOR IMAGING AND TREATMENT OF CANCER | Du Pont Pharmaceuticals Company (US) | 2001-01-17 | — | — | EP | disclosed |
| WO-1999051628-A1 | RADIOPHARMACEUTICALS FOR IMAGING INFECTION AND INFLAMMATION AND FOR IMAGING AND TREATMENT OF CANCER | DU PONT PHARMACEUTICALS COMPANY (US) | 1999-10-14 | — | — | WO | disclosed |