SCHEMBL28824040

SCHEMBL28824040

O=C1C=CN([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)[S+]([O-])N1

nearest known ligand 0.51

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ CDA P32320 8/20 0.44
▸ SLC28A1 O00337 1/20 0.44
▸ SLC28A2 O43868 1/20 0.44
▸ SLC29A1 Q99808 1/20 0.44
▸ SLC28A3 Q9HAS3 1/20 0.44
▸ MAPT P10636 1/20 0.42
▸ PYGM P11217 3/20 0.41
▸ PAX8 Q06710 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28824001 0.84 CDA (0.41) CDASLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL25380036 0.77 CDA (0.44) CDASLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL25381411 0.77 P2RY2 (0.53) —
SCHEMBL28580471 0.74 CDA (0.46) CDASLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL21283173 0.73 CDA (0.47) CDASLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL25458669 0.73 PYGM (0.44) CDASLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL15972109 0.72 TP53 (0.43) SLC28A1SLC28A2SLC29A1SLC28A3MAPT
SCHEMBL15972112 0.72 TP53 (0.43) SLC28A1SLC28A2SLC29A1SLC28A3MAPT
SCHEMBL18871272 0.71 CDA (0.48) CDASLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL31096857 0.68 CDA (0.42) CDASLC28A1SLC28A2SLC29A1SLC28A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114929288-A Synthetic modified RNA and uses thereof 西奈山伊坎医学院 2022-08-19 — — CN disclosed
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