SCHEMBL18871272

SCHEMBL18871272

O=C1C=CN([C@@H]2O[C@H](CO)C(O)C2O)C(S)N1

nearest known ligand 0.52

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ CDA P32320 8/20 0.48
▸ MAPT P10636 1/20 0.46
▸ SLC28A1 O00337 1/20 0.45
▸ SLC28A2 O43868 1/20 0.45
▸ SLC29A1 Q99808 1/20 0.45
▸ SLC28A3 Q9HAS3 1/20 0.45
▸ PYGM P11217 3/20 0.42
▸ LMNA P02545 1/20 0.40
▸ THRB P10828 1/20 0.40
▸ MTOR P42345 1/20 0.40
▸ MDM2 Q00987 1/20 0.40
▸ NCOA1 Q15788 1/20 0.40
▸ NCOA3 Q9Y6Q9 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21283173 0.86 CDA (0.47) CDAMAPTSLC28A1SLC28A2SLC29A1
SCHEMBL23867097 0.80 P2RY14 (0.62) —
SCHEMBL31543029 0.75 PYGM (0.40) CDAMAPTSLC28A1SLC28A2SLC29A1
SCHEMBL24487839 0.75 PYGM (0.40) CDAMAPTSLC28A1SLC28A2SLC29A1
SCHEMBL26798971 0.74 CDA (0.39) CDAMAPTSLC28A1SLC28A2SLC29A1
SCHEMBL28824040 0.71 CDA (0.44) CDAMAPTSLC28A1SLC28A2SLC29A1
SCHEMBL25458669 0.71 PYGM (0.44) CDAMAPTSLC28A1SLC28A2SLC29A1
SCHEMBL23353386 0.71 TK2 (0.37) CDASLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL21283066 0.71 TK2 (0.37) CDASLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL14510444 0.71 TK2 (0.37) CDASLC28A1SLC28A2SLC29A1SLC28A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10286086-B2 Alternative nucleic acid molecules and uses thereof MODERNATX, INC. (US) 2019-05-14 — — US disclosed
US-20170136131-A1 ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF Modema Therapeutics, Inc. (US) 2017-05-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170136131-A1 ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF NSUN2, RNGTT, NSUN3 CDA 78/4885MAPT 3589/4885SLC28A1 317/4885
US-10286086-B2 Alternative nucleic acid molecules and uses thereof NSUN2, RNGTT, NSUN3 CDA 78/4885MAPT 3589/4885SLC28A1 317/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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