Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | TARBP2 | Q15633 | 2/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.32 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23294320 | 0.88 | GRM1 (0.44) | NAMPT | |
| SCHEMBL23294376 | 0.74 | TARBP2 (0.47) | ALDH1A1MAPTCYP19A1TARBP2LMNA | |
| SCHEMBL29852210 | 0.74 | CA1 (0.42) | ALDH1A1MAPTKDM4ECYP19A1TARBP2 | |
| SCHEMBL23294523 | 0.74 | CA1 (0.42) | ALDH1A1MAPTKDM4ECYP19A1TARBP2 | |
| SCHEMBL17844418 | 0.73 | LIMK1 (0.34) | TRPV1ALDH1A1DGAT1 | |
| SCHEMBL23294443 | 0.73 | NPC1 (0.41) | ALDH1A1MAPTKDM4ETARBP2DGAT1 | |
| SCHEMBL3038011 | 0.72 | ALDH1A1 (0.50) | ALDH1A1MAPTKDM4ETDP1CYP1A2 | |
| SCHEMBL23294459 | 0.72 | TARBP2 (0.40) | ALDH1A1MAPTCYP19A1TARBP2CYP2C9 | |
| SCHEMBL23294312 | 0.71 | ALDH1A1 (0.34) | ALDH1A1MAPTKDM4ETARBP2DGAT1 | |
| SCHEMBL17844432 | 0.70 | TRPV1 (0.33) | TRPV1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114929676-A | Heterocyclic carboxylate compounds as glycolate oxidase inhibitors | 紫丁香疗法有限公司 | 2022-08-19 | — | — | CN | disclosed |