SCHEMBL28824192

SCHEMBL28824192

Fc1ccc2sc3ccc(Cl)cc3c2c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 4/20 0.51
TDO2 P48775 1/20 0.51
KDM4E B2RXH2 2/20 0.50
MPI P34949 4/20 0.46
MIF P14174 3/20 0.46
CYP2A6 P11509 3/20 0.41
ROCK1 Q13464 1/20 0.40
PHOSPHO1 Q8TCT1 2/20 0.40
PMM2 O15305 1/20 0.40
BCKDK O14874 1/20 0.39
G6PD P11413 1/20 0.37
PIM1 P11309 1/20 0.36
PIM2 Q9P1W9 1/20 0.36
ALDH1A1 P00352 1/20 0.36
CYP1A2 P05177 1/20 0.36
GAA P10253 1/20 0.36
CYP2C9 P11712 1/20 0.36
HPGD P15428 1/20 0.36
PSMB8 P28062 1/20 0.36
CYP2C19 P33261 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3159924 0.87 MPI (0.42) IDO1TDO2KDM4EMPIMIF
SCHEMBL29707472 0.87 MPI (0.42) IDO1TDO2KDM4EMPIMIF
SCHEMBL3258493 0.87 KDM4E (0.61) IDO1TDO2KDM4ECYP2A6ROCK1
SCHEMBL4732338 0.81 KDM4E (0.66) IDO1TDO2KDM4EMPIMIF
SCHEMBL11574923 0.81 KDM4E (0.61) IDO1TDO2KDM4EMPIMIF
SCHEMBL19114661 0.77 GPR3 (0.61) IDO1KDM4EMPICYP2A6PHOSPHO1
SCHEMBL3958418 0.77 KDM4E (0.72) IDO1KDM4ECYP2A6ROCK1G6PD
SCHEMBL29828808 0.77 KDM4E (0.72) IDO1KDM4ECYP2A6ROCK1G6PD
SCHEMBL24343663 0.75 KDM4E (0.50) IDO1TDO2KDM4EMIFCYP2A6
SCHEMBL11713878 0.75 KDM4E (0.50) IDO1TDO2KDM4ECYP2A6ROCK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114805295-A Method for purifying halogenated dibenzothiophene compound 江苏南大光电材料股份有限公司 2022-07-29 CN claimed
CN-114805295-A Method for purifying halogenated dibenzothiophene compound 江苏南大光电材料股份有限公司 2022-07-29 CN disclosed