SCHEMBL3958418

SCHEMBL3958418

Clc1ccc2sc3ccccc3c2c1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.72
GPR3 P46089 1/20 0.61
ALDH1A1 P00352 4/20 0.48
MAPT P10636 4/20 0.48
RAB9A P51151 2/20 0.48
HPGD P15428 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
IDO1 P14902 1/20 0.47
CYP1A2 P05177 1/20 0.44
LOXL2 Q9Y4K0 1/20 0.42
CYP2A6 P11509 1/20 0.42
JAK2 O60674 1/20 0.42
GAA P10253 1/20 0.42
HTT P42858 1/20 0.42
MAOB P27338 2/20 0.41
PTPN7 P35236 1/20 0.41
DUSP3 P51452 1/20 0.41
PTPN12 Q05209 1/20 0.41
PTPN22 Q9Y2R2 1/20 0.41
TDP1 Q9NUW8 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29828808 1.00 KDM4E (0.72) KDM4EGPR3ALDH1A1MAPTRAB9A
SCHEMBL23314362 0.92 KDM4E (0.64) KDM4EGPR3ALDH1A1MAPTRAB9A
SCHEMBL27394289 0.91 KDM4E (0.62) KDM4EGPR3ALDH1A1MAPTRAB9A
SCHEMBL3258493 0.89 KDM4E (0.61) KDM4EALDH1A1MAPTHPGDIDO1
SCHEMBL31012019 0.87 KDM4E (0.61) KDM4EGPR3ALDH1A1MAPTRAB9A
SCHEMBL15318107 0.87 KDM4E (0.61) KDM4EGPR3ALDH1A1MAPTRAB9A
SCHEMBL4692178 0.84 KDM4E (0.93) KDM4EGPR3ALDH1A1MAPTRAB9A
SCHEMBL37075 0.84 KDM4E (1.00) KDM4EGPR3ALDH1A1MAPTRAB9A
SCHEMBL10040873 0.84 KDM4E (0.54) KDM4EGPR3ALDH1A1MAPTRAB9A
SCHEMBL2341133 0.84 KDM4E (1.00) KDM4EGPR3ALDH1A1MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114464759-B Organic optoelectronic device and display device 三星SDI株式会社 2025-02-14 CN disclosed
US-12167689-B2 Heterocyclic compound and organic light emitting device comprising the same LG CHEM, LTD. (KR) 2024-12-10 US disclosed
US-11903311-B2 Heterocyclic compound and organic light emitting device comprising the same LG CHEM, LTD. (KR) 2024-02-13 US disclosed
US-20240023355-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2024-01-18 US disclosed
US-20240023355-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2024-01-18 US disclosed
US-20240023355-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2024-01-18 US disclosed
US-11800730-B2 Organic light emitting device LG CHEM, LTD. (KR) 2023-10-24 US disclosed
US-11787789-B2 Compound for an organic electric element, an organic electric element using the same, and an electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2023-10-17 US disclosed
US-11787789-B2 Compound for an organic electric element, an organic electric element using the same, and an electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2023-10-17 US disclosed
CN-116655589-A Preparation method of dibenzothiophene derivative 湖北尚赛光电材料有限公司 2023-08-29 CN disclosed
US-20070197677-A1 Sulfonium salt, curable composition, ink composition, inkjet recording method, printed material, process for producing lithographic printing plate, and lithographic printing plate FUJIFILM CORPORATION (JP) 2007-08-23 US disclosed
EP-0872903-B1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder SHINETSU CHEMICAL CO (JP) 2001-10-04 EP disclosed
US-6277519-B1 QUENCHING AN ALLOY MELT; COMMINUTION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2001-08-21 US disclosed
US-6096144-A TREATING WITH ACIDIC OR ALKALINE SOLUTION OF CONJUGATED UNSATURATED COMPOUND WITH AT LEAST 5 BONDS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2000-08-01 US disclosed
US-5858571-A TREATING A PULVERIZED HYDROGEN ABSORBING ALLOY WITH A SOLUTION COMPRISING A CONJUGATED UNSATURATED COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 1999-01-12 US disclosed
EP-0872903-A1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder Shin-Etsu Chemical Co., Ltd. (JP) 1998-10-21 EP disclosed
EP-0172427-B1 PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER Shin-Etsu Chemical Co., Ltd. (JP) 1989-07-05 EP disclosed
US-4758639-A Process for production of vinyl polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-19 US disclosed
US-4757124-A Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-12 US disclosed
EP-0172427-A2 Process for production of vinyl chloride polymer Shin-Etsu Chemical Co., Ltd. (JP) 1986-02-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240023355-A1 ORGANIC LIGHT EMITTING DEVICE CRY1, CRY2, CYP1A1 KDM4E 2823/4885GPR3 3580/4885ALDH1A1 5/4885
US-11787789-B2 Compound for an organic electric element, an organic electric element using the same, and an electronic device thereof PIEZO1, ORAI2, OCIAD1 KDM4E 1227/4885GPR3 4625/4885ALDH1A1 957/4885
US-11800730-B2 Organic light emitting device CRY1, CRY2, MAP1LC3C KDM4E 1575/4885GPR3 1898/4885ALDH1A1 237/4885
US-20070197677-A1 Sulfonium salt, curable composition, ink composition, inkjet recording method, printed material, process for producing lithographic printing plate, and lithographic printing plate SPIN2B, KAT2B, TIPRL KDM4E 135/4885GPR3 3472/4885ALDH1A1 2716/4885
US-11903311-B2 Heterocyclic compound and organic light emitting device comprising the same CYP1A1, CYP1B1, CHRM1 KDM4E 3276/4885GPR3 555/4885ALDH1A1 173/4885
US-12167689-B2 Heterocyclic compound and organic light emitting device comprising the same C1S, ARRB1, CRY1 KDM4E 3830/4885GPR3 189/4885ALDH1A1 321/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.