Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 1.00 |
| ▸ | MAPT | P10636 | 7/20 | 1.00 |
| ▸ | NPC1 | O15118 | 7/20 | 1.00 |
| ▸ | AHR | P35869 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | DHODH | Q02127 | 4/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 6/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29898269 | 1.00 | RAB9A (1.00) | RAB9ASMN1; SMN2MAPTNPC1AHR | |
| SCHEMBL12431830 | 0.86 | DHODH (0.77) | RAB9ASMN1; SMN2MAPTNPC1AHR | |
| SCHEMBL479805 | 0.86 | DHODH (0.76) | RAB9ASMN1; SMN2MAPTNPC1AHR | |
| SCHEMBL29133468 | 0.85 | RAB9A (0.74) | RAB9ASMN1; SMN2MAPTNPC1AHR | |
| SCHEMBL28824933 | 0.85 | RAB9A (0.76) | RAB9ASMN1; SMN2MAPTNPC1AHR | |
| SCHEMBL29898323 | 0.85 | RAB9A (0.76) | RAB9ASMN1; SMN2MAPTNPC1AHR | |
| SCHEMBL29421217 | 0.84 | RAB9A (0.73) | RAB9ASMN1; SMN2MAPTNPC1AHR | |
| SCHEMBL29898266 | 0.84 | RAB9A (0.78) | RAB9ASMN1; SMN2MAPTNPC1AHR | |
| SCHEMBL28949513 | 0.84 | RAB9A (0.78) | RAB9ASMN1; SMN2MAPTNPC1AHR | |
| SCHEMBL5083062 | 0.84 | RAB9A (0.72) | RAB9ASMN1; SMN2MAPTNPC1AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116574053-A | RIPK1 kinase target inhibitor and medical application thereof | 中国药科大学 | 2023-08-11 | — | — | CN | disclosed |
| CN-114989079-B | RIPK1 kinase target inhibitor and medical application thereof | 中国药科大学 | 2023-06-23 | — | — | CN | disclosed |
| CN-114989079-A | RIPK1 kinase target inhibitor and medical application thereof | 中国药科大学 | 2022-09-02 | — | — | CN | disclosed |