Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.74 |
| ▸ | MAPT | P10636 | 7/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.74 |
| ▸ | NPC1 | O15118 | 5/20 | 0.74 |
| ▸ | AHR | P35869 | 1/20 | 0.74 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 7/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.54 |
| ▸ | DHODH | Q02127 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28824955 | 0.85 | RAB9A (1.00) | RAB9AMAPTSMN1; SMN2NPC1AHR | |
| SCHEMBL29898269 | 0.85 | RAB9A (1.00) | RAB9AMAPTSMN1; SMN2NPC1AHR | |
| SCHEMBL479805 | 0.83 | DHODH (0.76) | RAB9AMAPTSMN1; SMN2NPC1AHR | |
| SCHEMBL28824933 | 0.82 | RAB9A (0.76) | RAB9AMAPTSMN1; SMN2NPC1AHR | |
| SCHEMBL29898323 | 0.82 | RAB9A (0.76) | RAB9AMAPTSMN1; SMN2NPC1AHR | |
| SCHEMBL29421217 | 0.82 | RAB9A (0.73) | RAB9AMAPTSMN1; SMN2NPC1AHR | |
| SCHEMBL29898256 | 0.82 | RAB9A (0.78) | RAB9AMAPTSMN1; SMN2NPC1AHR | |
| SCHEMBL28949513 | 0.82 | RAB9A (0.78) | RAB9AMAPTSMN1; SMN2NPC1AHR | |
| SCHEMBL29686385 | 0.81 | RAB9A (0.71) | RAB9AMAPTSMN1; SMN2NPC1AHR | |
| SCHEMBL23423252 | 0.79 | MAPT (0.68) | RAB9AMAPTSMN1; SMN2NPC1AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114671861-B | Wogonin derivative and preparation method and application thereof | 安徽医科大学 | 2023-11-24 | — | — | CN | disclosed |