Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 11/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 11/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 11/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 11/20 | 0.42 |
| ▸ | APH1A | Q96BI3 | 11/20 | 0.42 |
| ▸ | PSENEN | Q9NZ42 | 11/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PARL | Q9H300 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10598893 | 0.75 | CYP2D6 (0.46) | ALDH1A1KMT2AMAPK1MAPT | |
| SCHEMBL10681394 | 0.75 | CYP2D6 (0.46) | ALDH1A1KMT2AMAPK1MAPT | |
| SCHEMBL14750154 | 0.75 | CYP2D6 (0.46) | ALDH1A1KMT2AMAPK1MAPT | |
| SCHEMBL10879160 | 0.74 | MAPT (0.59) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL29111149 | 0.72 | MAPK1 (0.38) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL777222 | 0.72 | MAPK1 (0.47) | ALDH1A1KMT2AMAPK1MAPTPARL | |
| SCHEMBL14779168 | 0.72 | ALDH1A1 (0.49) | ALDH1A1KMT2AMAPK1MAPTPARL | |
| SCHEMBL9437100 | 0.71 | CRBN (0.43) | ALDH1A1KMT2AMAPK1MAPTPARL | |
| SCHEMBL14778503 | 0.71 | MAPK1 (0.46) | ALDH1A1KMT2AMAPK1MAPTPARL | |
| SCHEMBL14778152 | 0.71 | MAPK1 (0.46) | ALDH1A1KMT2AMAPK1MAPTPARL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114805078-B | Method for preparing 2,3, 4-trichloronitrobenzene through microchannel nitration | 上海农帆生物科技有限公司 | 2023-09-29 | — | — | CN | claimed |
| CN-115353458-B | Method for preparing aclonifen | 上海农帆生物科技有限公司 | 2023-09-29 | — | — | CN | disclosed |
| CN-114805078-B | Method for preparing 2,3, 4-trichloronitrobenzene through microchannel nitration | 上海农帆生物科技有限公司 | 2023-09-29 | — | — | CN | disclosed |
| CN-115353458-A | Method for preparing aclonifen | 上海农帆生物科技有限公司 | 2022-11-18 | — | — | CN | disclosed |
| CN-114805078-A | Method for preparing 2,3, 4-trichloronitrobenzene by micro-channel nitration reaction | 上海农帆生物科技有限公司 | 2022-07-29 | — | — | CN | disclosed |